L-Proline catalyzed one-pot synthesis of polysubstituted pyridine system that incorporates benzothiazole moiety via sustainable sonochemical approach

Haider Behbehani,Hamada Mohamed Ibrahim

Kuwait University, Kuwait

Posters & Accepted Abstracts: Chem Sci J

Abstract :

An efficient highly convenient synthesis of polysubstituted pyridine derivatives was established via the reaction of N-(benzothiazol-2-yl)-2-cyanoacetamides with an assortment of arylidene malononitrile or arylidene ethyl cyanoacetate in the presence of L-Proline as efficient organocatalyst for such type of ultrasonicmediated Michael addition. The mechanistic pathway and the factors affecting this reaction were also established. The main characteristics of this procedure are high yields, utilizing a cost-effective catalyst, ease of work-up and purification ways.

Biography :

Haider Behbehani has completed his PhD from Bath University, UK and Post-doctoral studies from Bath University School of Organic Chemistry. He is the Assistant Vice President for Research Analysis and Development. He has published more than 40 papers in reputed journals and has been serving as an Editorial Board Member of repute.

E-mail: drhaider.b@gmail.com