Opinion - (2025) Volume 14, Issue 5
Received: 01-Sep-2025, Manuscript No. aim-25-177774;
Editor assigned: 03-Sep-2025, Pre QC No. P-177774;
Reviewed: 17-Sep-2025, QC No. Q-177774;
Revised: 22-Sep-2025, Manuscript No. R-177774;
Published:
29-Sep-2025
, DOI: 10.37421/2427-5162.2025.14.592
Citation: Adeyemi, Samuel. ”Nutraceuticals for Holistic Disease Management and Well-being.” Alt Integr Med 14 (2025):592.
Copyright: © 2025 Adeyemi S. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution and reproduction in any medium, provided the original author and source are credited.
Nutraceuticals play a significant role in preventing and managing Type 2 Diabetes Mellitus. They include plant-derived compounds, vitamins, and minerals that modulate glucose metabolism, improve insulin sensitivity, and reduce inflammation. Integrating these natural compounds into management offers a promising adjunct to conventional therapies, potentially reducing disease progression and complications. [1].
This review examines nutraceuticals as a valuable complementary strategy for cardiovascular health, especially in older adults. Natural compounds like polyphenols and omega-3 fatty acids influence risk factors such as dyslipidemia and hypertension. These agents, when used appropriately, support heart health and reduce cardiovascular events as part of an integrated approach to wellness. [2].
A critical review investigates nutraceuticals in obesity and weight management. It assesses compounds like green tea extracts, capsaicin, and probiotics for their impact on appetite and fat metabolism. While some show promise, efficacy depends on dosage and individual factors. They are best utilized within a holistic weight loss strategy, including diet and exercise. [3].
Current evidence for anti-inflammatory nutraceuticals and their human health benefits is summarized. Compounds such as curcumin, omega-3 fatty acids, and various antioxidants modulate inflammatory pathways in chronic lifestyle disorders. These natural agents show potential for reducing systemic inflammation and supporting overall well-being, complementing conventional treatments. [4].
Nutraceuticals profoundly influence the gut microbiota, thereby impacting metabolic syndrome. This review highlights how prebiotics, probiotics, and plant-derived compounds beneficially alter the gut microbiome. This leads to improved glucose homeostasis, lipid metabolism, and reduced systemic inflammation. Targeting gut health with specific nutraceuticals is an integrative strategy for managing complexities. [5].
A systematic review evaluates clinical trials of nutraceuticals for brain health. It examines antioxidants, omega-3 fatty acids, and specific vitamins for supporting cognitive function, enhancing memory, and protecting against neurodegeneration. Insights into promising agents and areas needing further research emphasize evidence-based integration into brain health protocols for optimal function. [6].
Authors discuss the evidence and future outlook for nutraceuticals in managing lifestyle-related diseases. The article covers metabolic disorders and chronic inflammatory states, showing how bioactive food components offer therapeutic benefits. It highlights growing acceptance of nutraceuticals as part of an integrative approach, potentially preventing disease progression and improving patient quality of life. [7].
This paper focuses on polyphenols as nutraceuticals for metabolic syndrome management. It details how polyphenol compounds from fruits and vegetables exert antioxidant, anti-inflammatory, and glucose-lipid modulating actions. Incorporating polyphenol-rich foods and supplements contributes significantly to mitigating metabolic syndrome facets, offering a natural path toward better health outcomes. [8].
A systematic review and meta-analysis examines dietary supplements and nutraceuticals for anxiety and depression. It identifies compounds like omega-3 fatty acids, curcumin, and certain B vitamins showing promise. While not a standalone cure, these natural interventions can be a valuable part of an integrative treatment plan for improving mental well-being, complementing psychological support. [9].
This review details nutraceuticals role in cancer prevention and treatment. It explores how bioactive compounds from fruits and vegetables exhibit anti-cancer properties through antioxidant activity, cell signaling modulation, and apoptosis induction. Authors advocate integrating specific nutraceuticals into preventive strategies and as adjunctive therapies to enhance conventional treatments and reduce side effects. [10].
This article highlights the significant role nutraceuticals play in preventing and managing Type 2 Diabetes Mellitus. It discusses various plant-derived compounds, vitamins, minerals, and other bioactive substances, showing how they can modulate glucose metabolism, improve insulin sensitivity, reduce oxidative stress, and mitigate inflammation. The authors suggest that integrating these natural compounds into a comprehensive management plan offers a promising adjunct to conventional therapies, potentially reducing disease progression and complications. [1]. This review explores how nutraceuticals can serve as a valuable complementary strategy for maintaining cardiovascular health, especially in older adults. It delves into the mechanisms by which various natural compounds, like polyphenols, omega-3 fatty acids, and plant sterols, influence risk factors such as dyslipidemia, hypertension, and endothelial dysfunction. The authors emphasize that these agents, when used appropriately, can support heart health and reduce the incidence of cardiovascular events as part of an integrated approach. [2]. Heres a critical look at nutraceuticals in the context of obesity and weight management. The article examines the scientific evidence for various natural compounds, including green tea extracts, capsaicin, and probiotics, in their ability to impact appetite regulation, fat metabolism, and energy expenditure. It highlights that while some nutraceuticals show promise, their efficacy often depends on dosage, formulation, and individual factors, suggesting they are best utilized as part of a holistic weight loss strategy encompassing diet and exercise. [3]. This review summarizes the current evidence for anti-inflammatory nutraceuticals and their benefits for human health. It explores how compounds like curcumin, omega-3 fatty acids, and various antioxidants can modulate inflammatory pathways, which are often implicated in chronic lifestyle disorders. The article argues that these natural agents hold potential for reducing systemic inflammation and supporting overall well-being, suggesting their inclusion in dietary and health strategies to complement conventional anti-inflammatory treatments. [4]. What this really means is that nutraceuticals can significantly influence the gut microbiota, which in turn impacts metabolic syndrome. This review highlights how prebiotics, probiotics, and plant-derived compounds can beneficially alter the gut microbiomes composition and function, leading to improved glucose homeostasis, lipid metabolism, and reduced systemic inflammation. The authors make a strong case for targeting gut health with specific nutraceuticals as an integrative strategy to manage the complex aspects of metabolic syndrome. [5]. This systematic review critically evaluates clinical trials investigating nutraceuticals for brain health. It examines a range of natural compounds, including antioxidants, omega-3 fatty acids, and specific vitamins, for their potential to support cognitive function, enhance memory, and protect against neurodegenerative processes often linked to lifestyle factors. The review provides insights into the most promising agents and points to areas needing further research, emphasizing the importance of evidence-based integration into brain health protocols. [6]. Here, authors discuss the current evidence and future outlook for nutraceuticals in managing various lifestylerelated diseases. The article covers a broad spectrum of conditions, from metabolic disorders to chronic inflammatory states, showcasing how bioactive food components can offer therapeutic benefits by targeting underlying pathophysiological mechanisms. It highlights the growing acceptance of nutraceuticals as part of an integrative approach, acknowledging their potential to prevent disease progression and improve quality of life. [7]. This paper focuses on the specific role of polyphenols as nutraceuticals in the comprehensive management of metabolic syndrome. It details how various polyphenol compounds, found abundantly in fruits, vegetables, and herbs, exert their effects through antioxidant, anti-inflammatory, and glucose and lipidmodulating actions. The authors illustrate that incorporating polyphenolrich foods and supplements into a therapeutic regimen can significantly contribute to mitigating the multiple facets of metabolic syndrome, offering a natural path toward better health outcomes. [8]. This systematic review and metaanalysis examines the efficacy of dietary supplements and nutraceuticals in addressing anxiety and depression, common lifestylerelated mental health challenges. It synthesizes evidence from numerous studies, identifying specific compounds like omega-3 fatty acids, curcumin, and certain B vitamins that show promise in alleviating symptoms. The review suggests that while not a standalone cure, these natural interventions can be a valuable part of an integrative treatment plan for improving mental wellbeing. [9]. Lets break down the role of nutraceuticals in cancer prevention and treatment, a significant area within lifestylerelated disorders. This comprehensive review explores how various bioactive compounds, such as those found in fruits, vegetables, and spices, exhibit anticancer properties through mechanisms like antioxidant activity, modulation of cell signaling pathways, and induction of apoptosis. The authors argue for the integration of specific nutraceuticals into preventive strategies and as adjunctive therapies to enhance conventional cancer treatments and reduce side effects. [10].
Nutraceuticals present a promising frontier in the holistic management and prevention of various lifestyle-related diseases, ranging from Type 2 Diabetes Mellitus and cardiovascular ailments to obesity, chronic inflammation, and mental health challenges like anxiety and depression. These bioactive compounds, derived from plants, vitamins, minerals, and other natural sources, demonstrate diverse therapeutic effects. They can modulate glucose metabolism, enhance insulin sensitivity, reduce oxidative stress, mitigate inflammation, and positively influence the gut microbiota. Specific nutraceuticals, including polyphenols, omega-3 fatty acids, green tea extracts, capsaicin, probiotics, curcumin, and various antioxidants, have shown efficacy in supporting brain health, aiding weight management, and exhibiting anti-cancer properties. While not standalone cures, their integration into comprehensive health strategies, alongside conventional therapies, diet, and exercise, offers significant potential to improve patient outcomes, slow disease progression, and enhance overall well-being. Evidence-based research continues to support their role as valuable adjunctive interventions across multiple health domains.
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