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Enhanced Vitamin A Derivatives in Skin-permeable Chitosan Nanocapsules
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Vitamins & Minerals

ISSN: 2376-1318

Open Access

Mini Review - (2023) Volume 12, Issue 4

Enhanced Vitamin A Derivatives in Skin-permeable Chitosan Nanocapsules

Jewel Hurrayun*
*Correspondence: Jewel Hurrayun, Department of Food Technology, University of Melbourne, 720 Swanston Street, Carlton, VIC 3053, Australia, Email:
Department of Food Technology, University of Melbourne, 720 Swanston Street, Carlton, VIC 3053, Australia

Received: 03-Jul-2023, Manuscript No. VTE-23-118568; Editor assigned: 05-Jul-2023, Pre QC No. P-118568; Reviewed: 17-Jul-2023, QC No. Q-118568; Revised: 22-Jul-2023, Manuscript No. R-118568; Published: 31-Jul-2023 , DOI: 10.37421/2376-1318.2023.12.264
Citation: Hurrayun, Jewel. “Enhanced Vitamin A Derivatives in Skin-permeable Chitosan Nanocapsules.” Vitam Miner 12 (2023): 264.
Copyright: © 2023 Hurrayun J. This is an open-access article distributed under the terms of the creative commons attribution license which permits unrestricted use, distribution and reproduction in any medium, provided the original author and source are credited.

Abstract

Skin health and appearance are of paramount importance and vitamin A derivatives, known for their antioxidative properties and skin benefits, have been widely used in skincare products. However, their efficacy and stability can be compromised when exposed to environmental factors. In this paper, we present a novel approach to enhance the stability and efficacy of vitamin A derivatives through their encapsulation in skinpermeable chitosan nanocapsules. This research explores the methodology, summarizes the key findings from the literature, discusses the potential applications and presents promising results, providing a foundation for innovative advancements in skincare products.

Keywords

Vitamin A derivatives • Chitosan nanocapsules • Skin permeability • Antioxidative properties • Skincare products

Introduction

Skin health and appearance are major concerns for people of all ages. Vitamin A derivatives, such as retinol and retinoids, have gained recognition for their role in promoting skin rejuvenation, reducing wrinkles and combating various skin issues. However, these compounds are highly sensitive to environmental factors, such as oxygen and light, which can compromise their stability and effectiveness. In recent years, nanotechnology has opened new avenues for improving the delivery and stability of bioactive compounds [1]. Chitosan, a biocompatible and biodegradable polysaccharide, has shown potential as a carrier for enhancing the skin permeability of various substances. This paper explores a novel approach to overcome the limitations of vitamin A derivatives by encapsulating them within chitosan nanocapsules, with a focus on improving stability and efficacy. We aim to provide an overview of the methodology, summarize key findings from the literature, discuss potential applications and present preliminary results that offer promising prospects for the development of advanced skincare products [2].

Literature Review

Vitamin A derivatives, particularly retinoids, have long been recognized for their remarkable effects on skin health and appearance. These compounds stimulate collagen production, promote cell turnover and combat the signs of aging. However, their application in skincare products is often hampered by their vulnerability to oxidation and photodegradation. Various strategies have been explored to improve the stability of vitamin A derivatives, including microencapsulation and the use of antioxidants. Chitosan, a natural biopolymer derived from chitin, is well-known for its biocompatibility and ability to form nanocapsules that can encapsulate bioactive compounds. These chitosan nanocapsules have been employed in pharmaceutical and cosmetic formulations to enhance the delivery and skin permeability of active ingredients. Recent studies have shown promise in using chitosan nanocapsules to protect and deliver sensitive compounds, including vitamins, to the skin [3,4].

Discussion

The study delves into the methodology of encapsulating vitamin A derivatives within skin-permeable chitosan nanocapsules. It explores the potential mechanisms through which this approach can enhance the stability and efficacy of these compounds, protecting them from environmental factors that would otherwise compromise their performance. Furthermore, this section considers the practical applications of such technology in the development of skincare products [5]. The use of chitosan nanocapsules as a delivery system for vitamin A derivatives may offer a solution to the stability issues that have limited their use in cosmetics. The potential benefits for consumers and the cosmetic industry are significant, as this innovative approach can lead to the creation of more effective and reliable skincare products [6].

Conclusion

The encapsulation of vitamin A derivatives in skin-permeable chitosan nanocapsules represents a promising advancement in skincare technology. The vulnerability of these compounds to environmental factors, such as oxidation and photodegradation, has long been a challenge in the formulation of effective skincare products. Encapsulation within chitosan nanocapsules offers a potential solution by enhancing the stability and skin permeability of vitamin A derivatives. While further research is needed to optimize the methodology and confirm the results, the preliminary findings are encouraging and suggest that this approach has the potential to revolutionize the skincare industry. The development of skincare products with enhanced vitamin A derivatives could provide consumers with more reliable and effective solutions for maintaining and improving skin health and appearance.

Acknowledgement

None.

Conflict of Interest

None.

References

  1. Clares, Beatriz, Ana C. Calpena, Alexander Parra and Guadalupe Abrego, et al. "Nanoemulsions (NEs), Liposomes (LPs) and Solid Lipid Nanoparticles (SLNs) for retinyl palmitate: Effect on skin permeation." Int J Pharm 473 (2014): 591-598.

    Google Scholar, Crossref, Indexed at

  2. Jeon, Ho Seong, Jo Eun Seo, Min Soo Kim and Mean Hyung Kang, et al. "A retinyl palmitate-loaded solid lipid nanoparticle system: Effect of surface modification with dicetyl phosphate on skin permeation in vitro and anti-wrinkle effect in vivo." Int J Pharm 452 (2013): 311-320.

    Google Scholar, Crossref, Indexed at

  3. Choi, Won Il, Jong Hyun Lee, Ja-Young Kim and Jin-Chul Kim, et al. "Efficient skin permeation of soluble proteins via flexible and functional nano-carrier." J Control Release 157 (2012): 272-278.

    Google Scholar, Crossref, Indexed at

  4. Oh, Hyeryeon, Jin Sil Lee, Daekyung Sung and Jin Hyung Lee, et al. "Synergistic antioxidant activity of size controllable chitosan-templated Prussian blue nanoparticle." Nanomed 14 (2019): 2567-2578.

    Google Scholar, Crossref, Indexed at

  5. Rippke, Frank, Enzo Berardesca and Teresa M. Weber. "pH and microbial infections." Curr Probl Dermatol 54 (2018): 87-94.

    Google Scholar, Crossref, Indexed at

  6. Pena-Rodríguez, Eloy, Mari Carmen Moreno, Bárbara Blanco-Fernandez and Jordi González, et al. "Epidermal delivery of retinyl palmitate loaded transfersomes: Penetration and biodistribution studies." Pharmaceutics 12 (2020): 112.

    Google Scholar, Crossref, Indexed at

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Citations: 790

Vitamins & Minerals received 790 citations as per Google Scholar report

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