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Pharmacogenomics Articles Open Access | Open Access Journals
Journal of Pharmacognosy & Natural Products

Journal of Pharmacognosy & Natural Products

ISSN: 2472-0992

Open Access

Pharmacogenomics Articles Open Access

Lead compounds in drug discovery got to be optimized for both efficacy and safety. Unfortunately, a number of the adverse events associated with metabolism, clearance, transport and drug-drug interactions don't surface until much later in development. Similarly, cardiotoxicity, hepatotoxicity and idiosyncratic drug toxicity still haunt the drug development process. While new screening technologies, in vitro assays, in vivo models and computational tools are being developed and used, scientists are still unclear about when, where and which tools to use, how reliable the data is, and how predictive the translation is from in vitro to in vivo. Cambridge Healthtech Institute’s Advances in Drug Metabolism & Safety Testing conference looks at the scientific and technological progress being made to optimize lead compounds and predict drug-induced toxicities early in drug discovery, and to better translate these findings to the clinic. The talks and discussions highlight relevant case studies, recent research findings, and the use of innovative assays and technologies for improving drug safety.

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