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Open Access Articles On Congenital Nevi | Open Access Journals
Clinical Depression

Clinical Depression

ISSN: 2572-0791

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Open Access Articles On Congenital Nevi

The giant congenital melanocytic nevus is generally defined as a melanocytic lesion present at birth that will reach a diameter ≥ 20 cm in adulthood. Its incidence is estimated in <1: 20,000 newborns. Despite its rarity, this lesion is important because it can be associated with severe complications such as malignant melanoma, affect the central nervous system (neurocutaneous melanosis), and have a major psychosocial impact on the patient and his family due to his unsightly appearance. The giant congenital melanocytic nevus usually presents as a brown lesion, with a flat or wetted surface, well-defined borders and hypertrichosis. The congenital melanocytic nevus is above all a clinical diagnosis. However, congenital nevuses differ histologically from acquired nevi mainly by their larger size, the spread of nevus cells to the deeper layers of the skin and by their more varied architecture and morphology. Although the giant congenital melanocytic nevus is recognized as a risk factor for melanoma development, the precise extent of this risk remains controversial. The estimated lifetime risk of developing melanoma ranges from 5 to 10%. Because of these uncertainties and the size of the lesions, the management of the giant congenital melanocytic nevus must be individualized. Treatment may include surgical and non-surgical procedures, psychological intervention and / or clinical follow-up, with particular attention to changes in color, texture or the surface of the lesion. The only absolute indication for surgery in the giant congenital melanocytic nevus is the development of a malignant neoplasm on the lesion.

 

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Clinical Depression received 89 citations as per Google Scholar report

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