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Journal of Pharmacognosy & Natural Products

Journal of Pharmacognosy & Natural Products

ISSN: 2472-0992

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Natural Killer T Cells

Natural killer T cells (NKT) are a heterogeneous group of T cells that share the properties of T cells and natural killer cells. Many of these cells recognize the non-polymorphic CD1d molecule, an antigen-presenting molecule that binds to foreign and foreign lipids and glycolipids. They make up only about 0.1% of all T cells in peripheral blood. Natural killer T cells should not be confused with natural killer cells. The term "NK T cells" was used for the first time in mice to define a subset of T cells that expressed the marker associated with natural killer cells (NK) NK1.1 (CD161). It is now generally accepted that the term "NKT cells" refers to CD1d-restricted T cells, present in mice and humans, some of which jointly express a highly biased semi-invariant T cell receptor and cell markers NK.

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