Human Papillomavirus

Human papillomaviruses (HPVs) are little DNA tumor infections, some of which initiate harm in genital, butt-centric, head and neck and furthermore skin tissues. Vulval intraepithelial neoplasia (VIN) and cervical malignant growth are usually connected with human papillomavirus (HPV) type 16 contamination. This disclosure has given the chance to an immunotherapeutic way to deal with the treatment of these conditions. HPV contamination by at least one âÂ€Âœhigh-riskâÂ€Â or âÂ€ÂœoncogenicâÂ€Â types, most regularly 16 and 18, are available in 90-100% of obtrusive and grade 3 intraepithelial cervical injuries and in most of noncervical anogenital neoplasias. HPV oncogenes E6 and E7 assume a urgent job in lower genital tract carcinogenesis and are required for support of the changed state and harmful phenotype. This makes the HPV16 E6 and E7 oncoproteins appealing focuses for immunotherapy since they are only communicated in virally tainted and neoplastic cells, never in ordinary or solid cells. Assessment of Pre-Clinical Efficacy to HPV16 L2E6E7 Vaccine and HPV16 E6E7 Adenovirus-5 Vector Vaccine with Different Dosages and Prime-Booster Regiments in Mouse Model: Zhuang Fang-Cheng, Chen Gang, Wu Jie, Jin Su-feng, Jiang Yun-shui, Gao Men, Li Jian-buo, Zhao Li, Mao Zian and Tian Houwen

High Impact List of Articles

Conference Proceedings

Gene expression signatures identify novel regulatory genes and signaling pathways in young hypertensive patients making them susceptible to develop premature coronary heart disease
Salma Ahmadloo
Scientific Tracks Abstracts: Molecular and Genetic Medicine
Gene expression signatures identify novel regulatory genes and signaling pathways in young hypertensive patients making them susceptible to develop premature coronary heart disease
Salma Ahmadloo
Scientific Tracks Abstracts: Molecular and Genetic Medicine
Exome analyses in subfamily trios from large family tree in the south-eastern Moravia (Czech Republic) population with high incidence of parkinsonism
Radek Vodicka
Posters & Accepted Abstracts: Molecular and Genetic Medicine
Exome analyses in subfamily trios from large family tree in the south-eastern Moravia (Czech Republic) population with high incidence of parkinsonism
Radek Vodicka
Posters & Accepted Abstracts: Molecular and Genetic Medicine
Hydrogel scaffolds derived from decellularized extracellular matrices for tendon-to-bone tissue engineering
Noura Alom, Kevin M Shakesheff and Lisa J White
Posters-Accepted Abstracts: Journal of Tissue Science and Engineering
Hydrogel scaffolds derived from decellularized extracellular matrices for tendon-to-bone tissue engineering
Noura Alom, Kevin M Shakesheff and Lisa J White
Posters-Accepted Abstracts: Journal of Tissue Science and Engineering
A genomic approach to histamine function
Lucia Fernandez-Novoa, Ivan Tellado, Lola Corzo, Silvia Seoane, Ivan Carrera, Oscar Teijido, Juan C Carril and Ramon Cacabelos
Posters & Accepted Abstracts: Human Genetics & Embryology
A genomic approach to histamine function
Lucia Fernandez-Novoa, Ivan Tellado, Lola Corzo, Silvia Seoane, Ivan Carrera, Oscar Teijido, Juan C Carril and Ramon Cacabelos
Posters & Accepted Abstracts: Human Genetics & Embryology
Gene expression profiling of differentiating hematopoietic stem cells identifies transcriptional dysregulation in haematological malignancies
Wolf-K. Hofmann
Scientific Tracks Abstracts: Metabolomics:Open Access
Gene expression profiling of differentiating hematopoietic stem cells identifies transcriptional dysregulation in haematological malignancies
Wolf-K. Hofmann
Scientific Tracks Abstracts: Metabolomics:Open Access

Human Genetics & Embryology