Human Genetics & Embryology

ISSN: 2161-0436

Open Access

Yujing Li

615 Michael St, Atlanta, GA 30322

  • Review Article
    Regulation of Mirna Pathway and Roles of Micrornas in Tumorigenesis and Metastasis
    Author(s): Rong Jiang and Yujing LiRong Jiang and Yujing Li

    Although small non-coding RNAs, particularly microRNAs (miRNAs), small interference RNAs (siRNAs), and piwiinteracting RNAs (piRNAs), account for only a minor fraction of the expressed genome, they have been recognized as important regulators of gene and genome at post-transcriptional levels, functioning as RNA interference (RNAi) to regulate some of the most important biological processes in eukaryotic cells. Following the identification of the major components within the RNAi/miRNA pathway, some protein co-factors have been characterized to play significant roles in activity regulation of the RNAi/miRNA pathway in the last few years, suggesting that any regulators must be tightly regulated. It has been shown that microRNAs play vital roles in regulation of multiple signaling pathways and are involved in a variety of physiological and pathological processes. Given that high percentag.. Read More»
    DOI: 10.4172/2161-0436.S2-007

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