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Drug Resistance Of HIV | Open Access Journals
Journal of Biomedical Systems & Emerging Technologies

Journal of Biomedical Systems & Emerging Technologies

ISSN: 2952-8526

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Drug Resistance Of HIV

The ability of HIV to mutate and reproduce in the presence of antiretroviral drugs is called HIV drug resistance (HIVDR). The consequences of HIVDR include treatment failure and the spread of drug-resistant HIV. This can compromise the effectiveness of -hiv-aids/fact-sheets/21/56/drug- treatment options to reach the last 90 targets (achieve viral suppression) and further reduce the incidence of HIV, mortality and morbidity.

 

WHO is currently developing a new five-year global action plan for 2017-2021 to support a coordinated international effort to prevent, monitor and respond to the emergence of drug resistance to HIV, and to strengthen country efforts to meet global HIV targets.

Once a person is infected with HIV, the virus begins to multiply in the body. As HIV multiplies, it sometimes changes shape (mutates). Some HIV mutations that develop while a person is taking HIV drugs can lead to drug-resistant HIV.

Once drug resistance develops, the anti-HIV drugs that previously controlled the person's HIV are no longer effective. In other words, anti-HIV drugs cannot stop drug-resistant HIV from multiplying. Drug resistance can cause anti-HIV treatment to fail.

Drug-resistant HIV can spread from person to person (called transmitted resistance). People with transmitted resistance have HIV resistant to one or more anti-HIV drugs before they even start taking anti-HIV drugs.

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