Neurological Disorders

Computer Science and Artificial Intelligence Laboratory, Massachusetts Institute of Technology, USA

Publications

• Review   
  Potential Mechanisms for Human Genome Integration of Genetic Code from SARS-CoV-2 mRNA Vaccination: Implications for Disease
  Author(s): Anthony M. Kyriakopoulos, Peter A. McCullough, Greg Nigh and Stephanie Seneff*
  
  Background: The integration of genetic code from RNA viruses into host DNA, once thought to be a rare or even impossible phenomenon, is now recognized as probable. The Long Interspersed Nuclear Element (LINE)-1 mediated mechanism of insertion implies that many viral RNAs (apart from retroviral) can be reverse transcribed and then stably incorporated into DNA. Recombination between exogenous non-retroviral RNA and endogenous retroviral sequences that leads to reverse transcription and finally integration of the resulting cDNA into the host genome has been described. Recent data demonstrate that SARS-CoV-2 RNA sequences can be transcribed into DNA and may be actively integrated into the genome of affected human cells, mediated by retrotransposons. In some SARS-CoV-2 infected patient specimens, there is evidence for a large fraction SARS-CoV-2 sequenc.. Read More»
  DOI: 10.4172/2329-6895.10.10.519

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