Journal of Material Sciences & Engineering

ISSN: 2169-0022

Open Access

Rania M Salem

Department of Endodontics, Boston University, United States

  • Review   
    Stimulatory Role of Magnesium Chloride in Expression of Dentin Matrix Proteins
    Author(s): Rania M Salem*, Chang Zhang and Laisheng Chou

    Magnesium-based biomaterials might provide an innovative therapeutic potential to substantially enhance regeneration of dental tissues. In previous work, magnesium oxide (MgO) has been studied for its potential ability to enhance cell attachment, proliferation rate and dentin matrix protein expression of human dental pulp cells (HDPCs). However, to date, dentinogenic effect of magnesium chloride (MgCl2) on cell viability and expression of extracellular matrix proteins in HDPCs has not been investigated. This study was designed to compare the stimulatory effect of different concentrations of MgCl2 on dentinogenesis of HDPCs. HDPCs were cultured with 0.5 mM, 1 mM, 2 mM, 4 mM, 8 mM concentrations of supplemental MgCl2, 0 mM as negative control group. Stimulatory effect of MgCl2 was assessed by evaluating cell viability, and expre.. Read More»
    DOI: 10.37421/jme.2022.11.618

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