Environmental & Analytical Toxicology

ISSN: 2161-0525

Open Access

Nadielle Silva Bidu

Department of Biotechnology in Health and Investigative Medicine, Gonçalo Moniz Institute, Oswaldo Cruz Foundation/Fiocruz, Salvador, Bahia, Brazil

  • Commentary   
    Glycidyl Methacrylate as Probably Carcinogenic to Humans
    Author(s): Bruno Jose Dumêt Fernandes*, Silvana Trinchão Costa, Nadielle Silva Bidu and Ricardo David Couto

    Glycidyl methacrylate (GMA) is a monomer widely used in the production of dyes, paper, beverages, epoxy polymers, and others. It is a genotoxic substance with occupational exposure that can reach the general population by inhalation and skin contact. This agent may produce a large spectrum of DNA damage, evidenced by various carcinogenicity studies conducted on animals, and strong evidence of being carcinogenic in primary human cells. There is a deficit/absence of studies related to and no threshold limit value for GMA, however, due to the principles of similarity and precaution, it should be classified as a human carcinogen, and collective and personal control measures should be implemented or reviewed. This study provides an alert of GMA human exposure and its genotoxic and carcinogenic potential... Read More»

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