Journal of Pharmacognosy & Natural Products

ISSN: 2472-0992

Open Access

Mariusz Jaremko

Smart-Health Initiative (SHI) and Red Sea Research Center (RSRC), Division of Biological and Environ, King Abdullah University of Science and Technology (KAUST), Thuwal, Jeddah, Saudi Arabia

  • Research Article   
    Phytochemical Influence of Salvia officinalis L. from Saudi Arabia and Palestine on Oxidation and HIV Viral Load
    Author(s): Maryam A. Aljaziri, Dina Hajjar, Abdul-Hamid Emwas, Arwa A. Makki* and Mariusz Jaremko*

    Background: This study sought to identify and characterize the diverse flavonoids and phytochemical compounds in Saudi and Palestinian Salvia officinalis (sage) leaf extracts, and to evaluate their ability to inhibit protease enzymes, and thus their potential for use in antiretroviral drug discovery and development. We also explored sage’s ability to scavenge radicals; antioxidants derived from Lamiaceae plants play an important role in natural medicine. Methods: The crude extract of methanol and dichloromethane solvents from Saudi and Palestinian Salvia officinalis leaves (sage) were in vitro screened for inhibitory activity against HIV-1 protease. We examined antioxidant capacity against the synthetic radicals of 2,2′-azino-bis (3-ethylbenzothiazoline-6-sulfonic acid), identified the chemical constituents of the extracts by gas.. Read More»
    DOI: 10.37421/2472-0992.22. 8.185

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