Medicinal Chemistry

ISSN: 2161-0444

Open Access

Chaitrali Gosavi

Dr. D. Y. Patil College of Pharmacy, Akurdi, Pune-411044, Maharashtra, India

  • Mini Review   
    1,3,4-Thiadiazole and its Derivatives: A Versatile Moiety
    Author(s): Tejashree Deokule*, Chaitrali Gosavi and Aditya Sarode

    The evaluation of thiazole's biological activity, such as antibacterial, antiprotozoal, antitubercular, antifungal and anthelmintic, with an emphasis on their potential medicinal applications, is desirable because the thiazole has an important component effect on the pharmacophores of a large number of medicinally significant molecules. We are particularly interested in investigating newly synthesized aminothiazoles, particularly 2-aminothiazole derivatives, a class of heterocyclic ring systems with antiviral, antimicrobial, anticancer and anti-inflammatory properties, respectively. Numerous human cancer cell lines, including breast, leukemia, lung, colon, CNS, melanoma, ovarian, renal and prostate cell lines, were the subjects of previous in vitro anticancer evaluation studies of a variety of 2-aminothiazole analogs. In its use as a core structure in a variety of therapeutic appl.. Read More»
    DOI: 10.37421/2161-0444.2023.13.660

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