Chemical Sciences Journal

ISSN: 2150-3494

Open Access

AA El-Barbary

Department of Chemistry, Tanta University, Tanta, Egypt

  • Research Article   
    Synthesis, Characterization and Fluorescence of Novel Bromazepam Derivatives
    Author(s): AM Elessawy*, AA El-Barbary and Eman A ElBastawissy

    New bromazepam derivatives namely; 7-bromo-5-(pyridin-2-yl)-1,3-dihydro-2H-benzo[e] [1,4]diazepine -2-thione and 7-bromo-1-(4,6- dichloro-1,3,5-triazin-2-yl)-5-(pyridin-2-yl)-1,3-dihydro-2H-benzo[e] [1,4]diazepin-2-one have been prepared and characterized by spectroscopic methods (FT-IR, 1H-NMR, UV-visible and EI-mass). Furthermore, the fluorometric method has been developed to detect bromazepam in biological fluid. The new methods are based on measuring excitation and emission spectra of the reaction of bromazepam with cyanuric chloride in pyridine solution compared with excitation and emission spectra free bromazepam in methanolic solution... Read More»
    DOI: 10.37421/2150-3494.2023.14.329

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