Environmental & Analytical Toxicology

Šmerák P

Publications

• Research Article
  Antimutagenic Effect of the Ellagic Acid and Curcumin Combinations
  Author(s): Zoubková H, Šmerák P and Polívková ZZoubková H, Šmerák P and Polívková Z
  
  Introduction: There is an evidence to support the health benefits of diets rich in fruits, vegetables, legumes, whole grains and nuts. Plant-based foods are complex mixtures of bioactive phytochemicals. The potential health effects of individual phytochemicals, their combinations or combinations of phytochemicals and others drugs is studied in detail. Ellagic acid belongs to the group of bioactive polyphenols in fruit: strawberries, raspberries, grapes, black currant and walnuts. Curcumin is a natural compound extracted from the root of Curcuma longa plant. Methods: We perform in vitro Ames test and in vivo micronucleus test toward three mutagens/carcinogens, aflatoxin B1 and 2-amino-3-methylimidazo(4,5-f)quinoline and N-nitroso-N-methylurea to prove an antimutagenic effect of ellagic acid, curcumin and their combinations. Results: We verified the dose dependent antimu.. Read More»
  DOI: 10.4172/2161-0525.1000296

  Abstract PDF