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Journal of Biometrics & Biostatistics

ISSN: 2155-6180

Open Access

Perner A


Denmark

Publications
  • Review Article
    Count Data Analysis in Randomised Clinical Trials
    Author(s): Jakobsen JC, Tamborrino M, Winkel P, Haase N, Perner A, Wetterslev J and Gluud CJakobsen JC, Tamborrino M, Winkel P, Haase N, Perner A, Wetterslev J and Gluud C

    Choosing the best model for analysis of count data in randomised clinical trials is complicated. In this paper, we review count data analysis with different parametric and non-parametric methods used in randomised clinical trials, and we define procedures for choosing between the two methods and their subtypes. We focus on analysis of simple count data and do not consider methods for analyzing longitudinal count data or Bayesian statistical analysis. We recommend that: (1) a detailed statistical analysis plan is published prior to access to trial data; (2) if there is lack of evidence for a parametric model, both non-parametric tests (either the van Elteren test or the Tadap2 test, based on an aligned rank test with equal stratum weights) and bootstrapping should be used as default methods; and (3) if more than two intervention groups are compared, then the Kruskal–Wallis test m.. Read More»
    DOI: 10.4172/2155-6180.1000227

    Abstract PDF

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Citations: 3254

Journal of Biometrics & Biostatistics received 3254 citations as per Google Scholar report

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