Clinical Infectious Diseases: Open Access

ISSN: 2684-4559

Open Access

Nusrat Jamil


  • Research Article
    Viral and Bacterial Coinfection in Patients with Neurological Disorders: An Analytical Cross-Sectional Study from Karachi
    Author(s): Aneela Taj and Nusrat JamilAneela Taj and Nusrat Jamil

    To study the existence of coinfection of the meninges caused by Neisseria meningitidis, Herpes simplex virus-1 (HSV-1) and Herpes simplex virus-2 (HSV-2) in the CSF of patients admitted with neurological disorders. 92 CSF samples collected from patients having neurological ailments were subjected to the microbiological analysis for the detection of possible bacterial etiology. In order to screen the viral coinfection, DNA was extracted from the samples found positive for bacterial presence. Extracted DNA was amplified for the presence of glycoprotein G gene of HSV-1 and HSV-2. Of the 92 samples, 20 samples (21.7%) found infected with Neisseria meningitidis (Nm). PCR results highlighted that of this 20, 8 samples (40%) were found coinfected with both HSV-1 and HSV-2 in addition to the Nm. Whereas, 12 samples (60%) were found negative for the viral etiology. Moreover, out of 8 samples show.. Read More»

    Abstract PDF

Relevant Topics

arrow_upward arrow_upward