Journal of Bioanalysis & Biomedicine

Mike Kastura

Publications

• Research Article
  Bioencapsulation of Praziquantel in Adult Artemia
  Author(s): Matthew C. Allender, Mike Kastura, Robert George, Frank Bulman, Jason Yarborough and Sherry CoxMatthew C. Allender, Mike Kastura, Robert George, Frank Bulman, Jason Yarborough and Sherry Cox
  
  A description of bioencapsulation of praziquantel in adult Artemia for 2.5 g/L, 5 g/L, and 10 g/L treatment baths is presented. Praziquantel was detected in adult brine shrimp tissue after enrichment periods of 15 min, 30 min, 1 hr, 2 hr, 4 hr, 8 hr, 12 hr, and 24 hr. The assays were performed using high performance liquid chromatography. There was variable uptake by Artemia at all three bath treatments over time. Despite early variability, all three baths showed a terminal increase in praziquantel concentration. Highest concentration of praziquantel was seen in the initial sample (5 g/L) or the last sample (2.5 g/L and 10 g/L). The highest concentration of praziquantel at any one point was observed in the 5 g/L treatment bath at 15 minutes. Based on percentage, more praziquantel was incorporated into shrimp at the 10 g/L than either of the other treatment.. Read More»
  DOI: 10.4172/1948-593X.1000030

  Abstract PDF