Journal of Bioprocessing & Biotechniques

Kirsty McLachlan

Publications

• Research Article
  Qualitative Process Understanding Tools within Bioprocessing: A Case Study
  Author(s): Kirsty McLachlan, Charles Gordon and Jarka GlasseyKirsty McLachlan, Charles Gordon and Jarka Glassey
  
  Biotechnology is a key area of industrial interest and the importance of effective knowledge management for rapid bioprocess development, optimisation and operation is widely recognised as an important driver of biomanufacturing excellence. The Britest suite of tools and methodologies, designed to highlight knowledge gaps within chemical and physical processes, is explored as an approach to bioprocess knowledge acquisition and management. These tools can help identify where optimisation may be most beneficial, and also increase understanding of the process as a whole across a range of disciplines. This research identifies areas where Britest tools are not directly transferable into biotechnological applications, and formulates a whole bioprocess development methodology. The Britest tools have been considered using SuperPro Designer in relation to production of insulin using E. coli. S.. Read More»
  DOI: 10.4172/2155-9821.1000305

  Abstract PDF