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Clinical Depression

ISSN: 2572-0791

Open Access

Volume 8, Issue 6 (2022)

Mini Review Pages: 1 - 2

Adult Mice Chronically Exposed to THC during Adolescence do Not Change Their Anxiety-Like Behaviours Due to Impaired Ghrelin Signaling

Shanabrough Rania*

DOI: 10.37421/2375-2572-0791.8.34

Understanding the long-term impacts of marijuana usage is essential as adolescent marijuana use has been rising. According to earlier studies, marijuana use during adolescence raises the likelihood of mental disorders such schizophrenia, depression, and anxiety. The peptide ghrelin, which is largely generated in the gut, has a significant role in feeding behaviour. Recent research has demonstrated that ghrelin and the growth hormone secretagogue receptor, which is its receptor, are critical mediators of stress, anxiety, and depressive-like behaviours in animal models. Here, we examined the effects of persistent administration on anxiety-like behaviours in knockout mice and their wild-type littermates during late adolescence. Continuous exposure during late adolescence, according to our findings.

Mini Review Pages: 1 - 2

Pregnant Women Attending Tertiary Hospitals in Urban Centres in Nigeria: Depression, Anxiety and Stress Determinants

Ogba Tian*

DOI: 10.37421/2375-2572-0791.8.35

Pregnancy is typically regarded as a happy experience, but it also intensifies a woman's emotional and psychological state. Worldwide, some women experience mental illnesses, particularly in developing countries. There is proof that sadness, anxiety, and stress during pregnancy are very common in Nigeria. In order to determine the extent and contributing variables of depression, anxiety, and stress among pregnant women in Port Harcourt, Nigeria Between September and November 2022, two tertiary hospitals in Port Harcourt city undertook a facility-based crosssectional survey utilising the Depression Anxiety and Stress was used to conduct univariate, bivariate, and multivariate analyses. The statistical significance was determined at p 0.05 and the proportional odds model was applied.

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