Alternative & Integrative Medicine

The global pandemic of the corona virus disease (COVID-19) has caused widespread morbidity and mortality globally. The complicated pathophysiology of COVID-19 and lack of a single therapy have made management a significant issue. Through comprehensive pharmacological, toxicological and clinical research, AYUSH-64, a poly-herbal formulation developed by CCRAS, Ministry of AYUSH, Government of India, has demonstrated both its safety and effectiveness in treating infective febrile illnesses like malaria and influenza. Four components in AYUSH-64 include antiviral, immunomodulatory, anti-inflammatory, antipyretic and anti-inflammatory properties. In COVID-19, it stops the inflammatory responses that lead to substantial morbidity. The Government of India has also included AYUSH-64 in the National COVID management protocol based on Ayurveda and Yoga for asymptomatic and mild cases of COVID-19. The study summarizes the therapeutic potential of AYUSH-64 on the basis of clinical trials conducted in India on COVID-19.

Osteopathic Medicine is a branch of medicine that focuses on a holistic approach to patient care, emphasizing the importance of the musculoskeletal system and its relationship to overall health. Osteopathic physicians, also known as DOs, are licensed medical professionals who receive specialized training in the musculoskeletal system, as well as in the prevention and treatment of illness and injury.

Traditional medicine refers to the knowledge, skills and practices of indigenous and local communities worldwide, developed over centuries, for the prevention, diagnosis and treatment of physical and mental illnesses. This type of medicine is often based on natural remedies, including plant, animal and mineral products, as well as practices such as acupuncture, massage and meditation. Traditional medicine plays a significant role in many cultures, especially in developing countries, where it is often the primary form of healthcare available. Despite its widespread use, traditional medicine faces challenges, including the lack of standardization, scientific validation and regulation. As a result, efforts are underway to integrate traditional medicine into mainstream healthcare systems while ensuring its safety, efficacy and quality.

In India, for many cultures, the cow (or Kamadhenu) is a sacred animal. The current research set out to determine if cow urine concentrate made through total evaporation of cow urine retained any of its antimicrobial, antifungal, or anthelmintic properties. The disc diffusion method was utilized to examine antimicrobial activity against both Gram-positive and Gram-negative bacteria. Antifungal activity was evaluated against several Aspergillus species using the agar-well diffusion technique. An adult Indian earthworm model was used to study the anthelmintic activity. The CUC noticed a notable inhibition of Gram-positive bacteria. It was discovered that fungi inhibition was dose-dependent. Among the tested fungi, A. niger showed the greatest sensitivity. Worm mortality in the anthelmintic assay was found to be concentration dependent and CUC was found to have a more beneficial effect than the gold standard anthelmintic, piperazine citrate. The antibacterial and anthelmintic properties of CUC may be due to the presence of components. CUC can be used to treat conditions caused by opportunistic fungi, parasitic helminths and pathogenic bacteria. Isolation of inhibitory components and in vivo experiments require further study.

At the same time, ESRD patients with HD had a much reduced exercise capacity than ESRD patients without HD because of the illness, HD's side effects and deteriorating comorbidities. The indirect measurement of aerobic capacity and the oxidative capacity of peripheral muscle, known as the VO2 peak, was extensively utilised and was a powerful predictor of the survival time of ESRD patients. An earlier meta-analysis's findings, which suggested that consistent exercise was good for aerobic capacity, were inconsistent with this one. Exercise induced a rise in VO2 peak, a sign of enhanced aerobic capacity. Then, as a result of decreased fatigue, individuals with ESRD who are receiving HD may increase their activity time, abandon a sedentary lifestyle and finally see a decline in mortality.