Journal of Material Sciences & Engineering

Synthesis, structural, morphological, optical and biological evaluation of lanthanum oxide nanoparticles using co-precipitation methods.

Abstract

B. Ravindrana*, GK Kavi and J Balaji

Lanthanum nanoparticles have excellent photocatalytic, optical, physiochemical and biological properties and their applications are in modern society. Lanthanum nanoparticles were synthesized using a new and simple co-precipitation process. The structural and optical properties and the morphology of the produced nanocomposite were examined using X-Ray Diffraction (XRD) patterns, which confirm the development of hexagonal La2O3 nanoparticles with a structure. The presence of a LaO spectrum range of 4000 cm-1 to 400 cm-1 verifies the Fourier Transform Infrared (FTIR). Scanning Electron Microscopy (SEM) shows spherical-shaped particles in the 200 nm nano sized range. The optical characteristics of La2O3 nanoparticles were studied using UV-visible diffuse reflectance spectroscopy. The band gap value was determined to be 3.8 eV because, because of the metals, they can particularly target cancerous cells. Nanoparticles are increasing human exposure, particularly in medical applications and are currently being researched for their possible antibacterial and anticancer characteristics. The cytotoxicity of La2O3 was investigated using human cervical cancer cells (HeLa). The study also highlighted the potential use of La2O3 nanoparticles in cancer treatment due to their specific toxicity to cancer cells. Lanthanum has an IC50 value of 149.22 μg/ml for anticancer activity against the HeLa cell line.