Shanthakumar SP, Ivan Roberts M and George A
Post surgical wound healing is delayed and build intricacies in many patients because of clinical fomites. Vital instruments such as catheters and surgical blades are sterilized and used with immense care by the physicians. In spite of this due to low doubling time of the microbial pathogen multiplication and colonization on the instruments is inevitable, especially in longer surgical procedures, which still remains as a challenge for the clinicians and pathologists across the world. This study regarded isolation of anti-bacterial compound from beneficial bacteria and coating the purified compound on catheters and surgical blades by successive ionic layer adsorption and reaction method to prevent the surface contamination of clinical bacterial pathogen viz., Escherichia coli. After multiple modifications optimal precursor and required timing for coating was achieved and the coated tools provided antisurface colonization property. The compound was found to have no adverse drug reaction with higher affinity human protein receptors.
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Journal of Antimicrobial Agents received 444 citations as per Google Scholar report
