In this work, radon concentrations were measured in dwellings Kufa Technical institute, Iraq between November 2014 to February 2015 using time integrated passive radon dosimeters containing LR-115 Type II plastic track detectors. Also, we calculated the concentration of short-lived radon daughters, potential alpha energy, working level month, the annual effective dose rate, the annual equivalent dose rate and the excess lifetime cancer risk in all dwellings under study. The radon concentration in these dwelling ranges from (15.211 ± 2.745 to 32.445 ± 09.200) Bq/m3 with an average of (21.567 Bq/m3), which within the acceptable radon levels (50-150) Bq/m3 recommended by the International Commission on Radiological Protection (ICRP). The mean the excess lifetime cancer risk were found to be ranges from 35.458 to 75.633 with an average value of 50.297 per 106 persons. These values are within in the safe limits recommended by the international organizations.
Purpose: To compare findings in fluorine 18-fluorodeoxyglucose (FDG) positron emission tomography (PET) and computed tomography (CT) in patients with extra-nodal lymphoma by using a combined PET/CT scanner.
Methods and Materials: Between 2011 and April 2013, seventy seven patients with confirmed pathology of Hodgkin (32 patients) and Non Hodgkin lymphoma (45 patients) with extranodal involvement diagnosed at Nasser Institute Cancer Center (NICC), ministry of health, Cairo, Egypt. After collection of the two reports separately, combined reading was allowed afterwards, and the differences were recorded for our study. Results: PET-CT is very effective in detection of lesions in the bone and bone marrow, few patients may have CT finding without corresponding FDG uptake, CT without PET may be very effective in detecting recurrences in soft tissue, renal and GIT extrannodal lymphoma.
Conclusion: PET scan is more sensitive than the CT used alone, and the combination PET-CT can be considered the standard of care for detection of extranodal lymphomas excluding soft tissue, renal and GI lymphomas.
Purpose: Evaluate the knowledge and the attitude of the Togolese radiographers on the medical irradiation of pregnant women.
Materials and Methods: Cross-sectional study performed in April, 2011 about 72 radiographers of the public and private hospitals in Togo.
Results: The quarter of the radiographers thought that the MRI is an irradiant examination and 44.5% of them did not know that the scintigraphy uses ionizing radiations. There were 77.7% to consider that the pregnancy is not an absolved contraindication for any irradiant medical imaging modality. They thought in 88.8% of the cases that radiography must be realized only in the first ten days of the menstrual cycle of women old enough to procreate. The majority of the radiographers (72.3%) did not ask the date of last menstruation of the women before undergoing the examination. None recorded the exposure parameters used for the irradiation of the pelvis in young women. The great majority of the radiographers (86.1%) did not wear lead aprons for the pregnant women during the examinations and 83.3% of them have already refused to realize an unjustified radiography to the pregnant women. Globally, the erroneous knowledge on the biological effects of ionizing radiations and on radiation protection rules of the pregnant woman, were more counted with radiographers having more than 10 years of work experience.
Conclusion: It is concluded that the Togolese should take special attention to standard for women exposed to ionizing radiation. In-service training in radiation protection of the patients should be encouraged in Togo.
Objective: To evaluate prospectively the early cardiac changes from doxorubicin based chemotherapy and radiotherapy in breast cancer patients.
Methods and Materials: 56 patients with early or locally advanced breast cancer were included in the study. ECG, ECHO and Equilibrium Radionuclide Ventriculography (ERV) was done at baseline, after chemotherapy, after radiotherapy and at 6 months of follow up.
Results: In Group 1 patients who completed six cycles of chemotherapy before starting radiation, the mean LVEF decreased after chemotherapy and after RT(from 66.79 ± 3.73 to 63.45 ± 3.54 and 61.64 ± 4.26, p<0.05). In Group 2 patients who received six cycles of chemotherapy after completion of radiotherapy, mean LVEF decreased post RT and post chemotherapy (from 66.67 ± 4.33 to 66 ± 4.975 and 62.7 ± 2.92, p<0.05).In Group 3 patients also who received neoadjuvant chemotherapy, radiation and adjuvant chemotherapy there was a decline in mean LVEF.In Group 4 patients who received only adjuvant chemotherapy mean LVEF decreased after chemotherapy (from 67.25 ± 4.33 to 64.75 ± 2.062, p<0.05).
LVEF was also measured by MUGA/ERV. In Group 1, mean LVEF decreased after chemotherapy and RT (from 58.14 ± 2.997 to 56.15 ± 3.144 and 56.21 ± 3.81, p<0.050. In Group 2 mean LVEF decreased after RT and chemotherapy (from 59.11 ± 1.41 to 58.67 ± 2.872 and 54.44 ± 1.81, p<0.05).In Group 3 patients, there was a decline in mean LVEF post neoadjuvant chemotherapy, after radiation and after adjuvant chemotherapy. In Group 4 mean LVEF decreased after chemotherapy (from 60 ± 1.63, to 58.75 ± 1.89, p<0.05).
Conclusion: Our prospective study shows that a significant number of patients can develop a significant transient depression in ventricular function acutely after chemotherapy and radiotherapy as demonstrated by a decrease in LVEF by conventional ECHO and ERV scan.