Immunosensors are compact analytical devices in which the event of formation of antigen-antibody complexes is detected and converted, by means of a transducer, to an electrical signal, which can be processed, recorded and displayed. Different transducing mechanisms are employed in immunological biosensors, based on signal generation (such as an electrochemical or optical signal) or properties changes (such as mass changes) following the formation of antigen-antibody complexes. In this chapter, the basics of immunosensors are presented focused on the different transduction techniques used in immunosensing.
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Brain Stimulation, Biochimica et Biophysica Acta - Biomembranes, FEBS Letters, Biochimica et Biophysica Acta - General Subjects, Medical Physics