The use of isomeric normal and abnormal palladium NHC complexes in direct C5-arylation reaction

5^th International Conference on Organic and Inorganic Chemistry

July 12-13, 2018 | Paris, France

Yan-Yi Lee and Hon Man Lee

National Changhua University of Education, Taiwan

Posters & Accepted Abstracts: J Chemical Sci

Abstract :

We designed four series of isomeric palladium(II) complexes with normal and abnormal N-Heterocyclic Carbenes (NHCs) ligands. These complexes were characterized by 1H and 13C NMR spectroscopy, elemental and X-ray crystallography. Their potential application as catalysts in direct C5-arylation reaction between imidazoles and aryl halides were investigated. Using a mere 0.5 mol % Pd loading, coupled products were obtained with moderate to excellent yields. Normal NHCs complexes have better catalytic activity than their abnormal counterpart. DFT calculations were performed to explain the difference.