Role of mass spectrometry in pharmaceuticals

Alternative & Integrative Medicine

ISSN: 2327-5162

Open Access

Role of mass spectrometry in pharmaceuticals

Rashid Mahmood

Surge Labs, Pakistan

Scientific Tracks Abstracts: Altern Integr Med

Abstract :

Mass spectrometry is an analytical technique to measure the molecular or atomic weight of samples. Mass spectrometer is an instrument that produces charged molecular species in vacuum, separates them by means of electric and magnetic fields and measures the mass-to-charge ratios and relative abundances of the ions thus produced. It is being increasingly used for detection and analysis of proteins from complex samples. Mass spectrometry has emerged as a powerful analytical tool applied to the health life sciences and the pharmaceutical sector. The use of Mass Spectrometry in the pharmaceutical sector associated with the Drug Discovery and Development process is rich and varied. Many of the initial efforts were associated with online high performance liquid chromatography-mass spectrometry in drug metabolism, pharmacokinetic and pharmacodynamic studies. Pharmacokinetic studies with Mass Spectrometry can provide quantitative information about a compounds half-life in the body and how quickly it is metabolized or excreted. The increase in sensitivity and resolution of the Mass Spectrometer has opened new dimensions in analysis of pharmaceuticals and complex metabolites of biological systems. Compared with other techniques, mass spectroscopy is only the technique for molecular weight determination, through which we can predict the molecular formula. It is also used as a sensitive detector for chromatographic techniques like LC-MS and GC-MS.

Biography :

Rashid Mahmood has Master’s degree in Analytical Chemistry and MS in Total Quality Management. He has 14 years of experience of pharmaceutical quality operations and has participated in many international conferences as a keynote speaker. Currently he is working as a Senior Executive Manager, Quality Operations for Surge Lab, Pakistan engaged in the manufacturing of microencapsulated APIs, liquid & dry powder parenterals.



Google Scholar citation report
Citations: 413

Alternative & Integrative Medicine received 413 citations as per Google Scholar report

Alternative & Integrative Medicine peer review process verified at publons

Indexed In

arrow_upward arrow_upward