Recent treatments for cardiac arrhythmias: Confusion of ganglionated plexi (GP), fibrosis and myocardial structural diseases areas, leading to similarity of detected signals (complex atrial fractionated electrograms)

2^nd International Conference on Neuroimmunology & Therapeutics

December 01-02, 2016 Atlanta, USA

Marc Mounir Rahme

Ottawa University, USA

Posters & Accepted Abstracts: J Neurol Disord

Abstract :

Atrial Fibrillation (AF) is a major life threatening disease which is still refractory to all pharmaceutical compounds. Catheter ablation procedure is currently used as an �easy and safe� clinical intervention targeting the early activation sites that are triggering the initiation of arrhythmias. However, the catheter ablation procedure is still considered as ineffective treatment for long-term curing of arrhythmias and for preventing their recurrences. Despite the high technologies for mapping, detecting and delivering the right energy sources to any location in the human cardiac heart chambers insulating the right triggers areas for AF still the main challenges to all currently existing devices companies (ex. Biosense Webster (subsidiary of J&J; Carto Solution), St Jude Medical Inc, (Ensite system), Boston Scientific, Medtronic (with Cryocath Technologies, Atricure Inc, etc). Detecting the sites of early activations and the locations of the triggers ganglia are still confused with other structural diseases such as fibrosis, which are limiting those devices to achieve the detection of the right hit (ex. triggering GP). Thus, it adds complications and risks to the long-term inefficacy of the catheter ablation procedure, in addition to major side effects and complications to this minimally invasive clinical procedure. �NerveC� is developing a high end assembly able to detect selectively the GPlocations. Thus, it will limit the confusion during mapping of the heart for electrophysiological (EP) study and for catheter ablation procedure for offering long-term cure from cardiac arrhythmias, such as atrial fibrillation, a major disease that affects our aging population. Therefore, by introducing �NerveC� to the EP clinical practice will help to detect selective EP signals generated by the autonomic nerve (=GP) using the FFT (Fast Fourier Transformation), offering a unique method to specifically targeting the rotors triggering the cardiac AF.

Biography :

Email: Mrahme@uottawa.ca