Pregnancy in women with renal transplant

International Conference and Exhibition on Nephrology & Therapeutics

August 20-22, 2012 Hilton Chicago/Northbrook, USA

Dinkar Kaw

Scientific Tracks Abstracts: J Nephrol Therapeut

Abstract :

P regnancy is uncommon in women with end stage renal disease because of impaired fertility. Renal transplant restores fertility & successful pregnancies have been reported in women with renal transplant. Pregnancy usually has no adverse effect on renal graft function and survival in women with normal renal graft function. However, pregnancy should be considered high risk in patients with renal transplant due to higher than normal incidence of hypertension & Pre-eclampsia. The outcome is not so favorable in patients who have some renal graft dysfunction at the time of conception which is comparable to outcome in chronic kidney disease patient with similar renal function. In addition, fetal outcome is not favorable with higher than normal incidence of intrauterine growth restriction and prematurity. Predictors of successful pregnancy outcome in renal transplant recipient are good general health for about 2 years after transplantation, good stable renal allograft function, and no recent episode of acute rejection, no evidence of ongoing rejection, normal blood pressure or minimal anti-hypertensive regimen, absence of or minimal proteinuria and absence of pelvi- calyceal dilatation on allograft ultrasound