Medicinal Chemistry

ISSN: 2161-0444

Open Access

Phytochemicals and antioxidant capacities from Dacryodes rostrata fruits

3rd International Conference on Medicinal Chemistry & Computer Aided Drug Designing

December 08-10, 2014 DoubleTree by Hilton Hotel San Francisco Airport, USA

Prasad K N, Tee L H, Ramanan R N, Tey B T, Chan E S, Azrina A, Amin I, Yang Bao and Lau C Y

Scientific Tracks Abstracts: Med Chem

Abstract :

Dacryodes rostrata is an indigenous fruit found in Sarawak, Malaysia. The fruit is ovoid in shape, purple colour and rich in oil, protein and minerals and used as food by the local communities. In this work, antioxidant components and antioxidant capacities of the extracts of peel, pulp and seeds of D. rostrata were evaluated. Total phenolic (1007?24 mg/g GAE DW) and flavonoid contents (2550?37 mg/g QE DW) of the seed extracts were higher when compared to peel and the pulp extracts. In addition, 1, 1-diphenyl-2-picryl hydrazyl (DPPH) free radical scavenging activity of the seed extracts were higher (65%), compared to peel (52%) and pulp (19%). Ferric reducing antioxidant power (FRAP) values of the seeds (1.22 mM FeSo4 equivalent) exhibited highest activity when, compared with peel (0.23 mM FeSo4 equivalent) and pulp (0.10 mM FeSo4 equivalent). Seed extract also showed highest total antioxidant capacity determined by phosphomolybdenum method. Liquid chromatography-mass spectra (LC-MS) of the seed extracts from D. rostrata revealed the presence of phytochemicals in the form of gallic acid, ellagic acid, epicatechin, kempferol and quercetin. Thus, D. rostrata seed extracts is having potent antioxidant capacity and could be used as a natural source of antioxidants.

Biography :

Prasad K N is a Senior Research Fellow at Chemical Engineering Discipline, School of Engineering, Monash University Malaysia. He obtained his PhD degree in Botany in India and worked as Post-Doctoral Researcher in China and in Malaysia. He has published over 50 international publications and 6 book chapters with h-index of 17. Currently, he has supervising Honours, Masters and PhD students. His research interest includes food chemistry, antioxidants, nutraceuticals, food processing and food composition.

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