New developments in the Castagnoli-Cushman reaction toward drug disoceovery and lead generation

European Chemistry Congress

June 16-18, 2016 Rome, Italy

Mikhail Krasavin

Saint Petersburg State University, Russia

Posters & Accepted Abstracts: Chem Sci J

Abstract :

The Castagoli-Cushman reaction is firmly establishing itself as the mainstream in multi-component chemistry. More recent contributions from our group not only advanced the heterocyclic product space accessible by this reaction to a completely new level but also gained some mechanistic insight into this important reactions. This, in turn, has allowed us making this reaction a far for amenable to plant setting and green chemisty standards. A number of drug leads have also emerged from these efforts which will be of interest to a wider durg discovery-minded audience. mkrasavin@hotmail.com