El Kaoui Habiba
University Ibn Tofail, Morocco
Scientific Tracks Abstracts: J Neurol Disord
Introduction: The deregulation of the energy balance by the malnutrition leads to the dysfunction of the neuro- The metabolic
mechanisms but these homeostatic problems can be corrected by nutritional supplements. In this study, we investigated the
effects of flaxseed on metabolism and anxiety- depressive-like disorders in high fructose-fed (23%) Wistar rat.
Methods: One-month-old female Wistar rats were divided into four groups of six rats:1. Control: (30g of standard food + 30ml
of tap water), 2. Control supplemented with flaxseed (27g standard food + 7g flaxseed + 30ml tap water) 3. Fructose (30 g
standard food + 23% fructose) 4. Fructose supplemented with flaxseed (23 g standard food + 7gflaxseed + 23% fructose), after
two months of diet, the rats underwent a battery of tests to evaluate the affective behavior (Open Field, Elevated Plus Maze and
Forced Swimming Test) and biochemical analyzes of glucose, cholesterol and triglycerides
Results: High fructose diet inducesadverse metabolic effects (increases blood sugar, cholesterol, triglycerides) and behavioral
ones(depression). Forflaxseed, it does not correct anxiety, but decreases depression-like and metabolic disorders.
Conclusion: Our results suggest that a high fructose diet induces metabolic and behavioral dysfunctions. Flaxseeds have
improved these conditions.
El Kaoui Habiba completed her master's degree at the age of 25 from the University ibn tofail Morocco and is currently doing her doctoral studies at the same faculty. She has published a book titled "Effects of Flaxseed on the Pathophysiology of Obesity and Behavioral Disorders following a High Fructose Diet in Wistar Rats" in an "OmniScriptum" editing group.Presenting author details.
E-mail: habibaelkaoui@gmail.com
Neurological Disorders received 1253 citations as per Google Scholar report
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