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Follow up on anal Pap-smear in HIV-positive and negative patients
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Journal of AIDS & Clinical Research

ISSN: 2155-6113

Open Access

Follow up on anal Pap-smear in HIV-positive and negative patients


4th International Conference on HIV/AIDS, STDs and STIs

October 03-05, 2016 Orlando, Florida, USA

Sylvia Heloisa Arantes Cruz and Cristiano Ricardo Siqueira de Souza

Faculdade de Ci�ªncias M�©dicas da Santa Casa de S�£o Paulo, Brazil
Universidade de Sao Paulo, Brazil
Centro de Refer�ªncia e Tratamento DST Aids, Brazil

Scientific Tracks Abstracts: J AIDS Clin Res

Abstract :

HPV infection is responsible for warts and carcinoma in genital area. Almost 80% of the sexual active population is infected with at least one serotype. The cervix Pap smear is collected for the prevention of the cervix cancer performing a similar technique we are able to prevent anal cancer collecting anal Pap-smear. The rates of anal cancer are increasing since the start of HIV epidemic. The anal intercourse seems to be extremely related to HPV infection. Anal dysplasia is described as a precursor of anal squamous carcinoma, so anal cancer has been screened with anal Pap-smear protocol, high-resolution anoscopy and high-risk HPV DNA test. The aim of this study is to compare the findings of the screening with anal Pap-smear in 38 HIV-positive and negative patients from January 2014 to December 2015 at CRT/AIDS, S�£o Paulo who previously had anal intercourse. The first anal Pap-smear sample was collected in 2014 and the second in 2015. The anal lesions were treated with 90% trichloroacetic acid (TCA) and 5% imiquimod for 12 weeks. The statistical analysis was performed using chi-square test and the significance level was set at less than 5%. 38 patients were evaluated, 28 were infected with high risk HPV; 10 of them presented improvement in anal Pap-smear after one year. We concluded that anal dysplasia was more common in HIVpositive patients and that high-risk HPV infection was related to anal dysplasia.

Biography :

Sylvia Heloisa Arantes Cruz has completed her PhD from Santa Casa de São Paulo, Brazil. She is an Assistant Professor at Santa Casa de São Paulo, Brazil and at CRT/AIDS São Paulo, Brazil. Her research is on screening anal cancer in HIV-positive patients.

Email: sylviahacruz@hotmail.com

Google Scholar citation report
Citations: 5061

Journal of AIDS & Clinical Research received 5061 citations as per Google Scholar report

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