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Endovascular management for tandem occlusions of anterior circulation: Systematic analysis of 99 patients from literature
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Neurological Disorders

ISSN: 2329-6895

Open Access

Endovascular management for tandem occlusions of anterior circulation: Systematic analysis of 99 patients from literature


2nd International Conference on Neurological Disorders and Stroke

April 28-30, 2016 Dubai, UAE

Ibrahim Al Naami, Abdelaziz Sagga and Faris Al Ebdi

King Khalid University, Saudi Arabia
King Fahad Medical City, Saudi Arabia

Scientific Tracks Abstracts: J Neurol Disord

Abstract :

Introduction: This study was conducted to review and compare the endovascular therapies to treat tandem occlusions of anterior cerebral circulation in the setting of acute ischemic stroke. Materials & Method: Literature review was carried out using Pub-Med. We reviewed studies that described endovascular management for patients with tandem occlusions/stenoses of extra-cranial and intracranial arteries of the anterior cerebral circulation. Results: 99 patients were included. The median NIHSS (for 97 patients) at the time of admission was 16 (SD�±5.5). The mean times and ranges from onset of symptoms to recanalization (for 46 patients) and from groin to recanalization (for 54 patients) were 412 minutes (Range: 120-1574) and 83 minutes (Range: 14-180), respectively. The mean outcome mRS (for 97 patients) was 2.39 (SD�±2.2) and 61.9% of patients had mRS of â�¤2 at 90 days. 81.25% of patients who had mRS of â�¤2 had groin to recanalization time of less than 90 minutes (p-value: 0.018). Despite that only 7% of patients underwent retrograde approach, 85.7% of them had outcome mRS of â�¤2 compared to 60% of patients with anterograde approach (p-value: 0.016). TICI scale was described for 72 patients, 77.8% of them had scale of â�¥2b. 95.8% (23 patients) who received intravenous t-PA had TICI scale of â�¥2b while 75.7% (25 patients) who did not receive IV t-PA had same TICI scale (p-value: 0.041). 13.9% of patients experienced cerebral hemorrhage. Conclusion: Groin to recanalization time of less than 90 minutes and the retrograde approach have shown to be favorable prognostic factors based on mRS. The use of IV t-PA has been associated with higher TICI scales.

Biography :

Email: ialnaami@gmail.com

Google Scholar citation report
Citations: 1253

Neurological Disorders received 1253 citations as per Google Scholar report

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