Effect of an Intermittent Photic Stimulation (IPS) on Electroencephalogram (EEG) of females with premenstrual dysphoric disorders

12^th Global Neurologists Meeting on Neurology and Neurosurgery

September 21-22, 2018 Singapore

Binu Shrestha, Bishnu Hari Paudel, Nirmala Limbu and Kopila Agrawal

Trinity School of Medicine, St. Vincent and the Grenadines
B.P. Koirala Institute of Health Sciences, Nepal
Birat Medical College Teaching Hospital, Nepal

Posters & Accepted Abstracts: J Neurol Neurosci

Abstract :

Many women with regular menstrual cycles report unpleasant physical and/or psychological symptoms just before the menstrual cycle begins. For many women, these symptoms are mild and tolerable. However, for some women, these symptoms can be disabling and may cause significant disruption in their lives and are often reasons for seeking a medical treatment. These symptoms together are called as Premenstrual Syndrome (PMS), and with the modern concept, the severe form of PMS is named as Premenstrual Dysphoric Disorders (PMDD). The study was conducted on thirty females with PMDD, selected on the basis of inclusion and exclusion criteria, and research criteria, Diagnostic and Statistical Manual of Mental Disorders, 4th Edition (DSM-IV). All the participants were explained about the procedure and written consent was taken. Anthropometric and cardio respiratory variables were recorded followed by EEG recordings with 5, 10, 15, 20, 25, 30 Hz frequencies of intermittent photic stimulation. The first recordings were taken before menses started or during peak of symptoms reported and were repeated immediately after menses were over. EEG recordings were dissected out into its constituent frequency bands by Fast Fourier Transformation. The data of EEG power spectra were non-normally distributed, hence subjected to log transformation and statistical analysis was done. The EEG power spectra were expressed as mean ± standard deviation. Paired sample t test was used to compare the anthropometric, cardio-respiratory variables, and the premenstrual EEG power spectra with post menstrual EEG power spectra. The premenstrual EEG power spectra or the EEG power spectra during the peak of symptoms as compared to the postmenstrual EEG power spectra showed a significant (p<0.05) increase in beta activity over frontotemporoparietal (F3, C3, T3 and P3) area of left hemisphere which concludes that the increased in beta activity at most of the sites of left hemisphere under intermittent photic stimulus before menses or during the peak of symptoms of PMDD is indicative of presence of anxiety, stress, insomnia and obsessive or negative thought.

Biography :

E-mail: bshrestha@trinityschoolofmedicine.org