Computational Drug design and synthesis of Pharmacophore based hybrid Oncological molecules

7^th Pharmaceutical Chemistry Conference

May 24-25, 2022 | Webinar

Isham Alzoubi

Department of Surveying and Geomatics Engineering, Syria

Scientific Tracks Abstracts: Med Chem (Los Angeles)

Abstract :

The aim of this work was to determine best linear model Adaptive Neuro-Fuzzy Inference System (ANFIS) and Sensitivity Analysis in order to predict the energy consumption for land leveling. In this research effects of various soil properties such as Embankment Volume, Soil Compressibility Factor, Specific Gravity, Moisture Content, Slope, Sand Percent, and Soil Swelling Index in energy consumption was investigated. The study was consisted of 90 samples were collected from 3 different regions. The grid size was set 20 m in 20 m (20*20) from a farmland in Karaj province of Iran. The values of RMSE and R2 derived by ICA-ANN model were, to Labor Energy (0.0146 and 0.9987), Fuel energy (0.0322 and 0.9975), Total Machinery Cost (0.0248 and 0.9963), Total Machinery Energy (0.0161 and 0.9987) respectively, while these parameters for multivariate regression model were, to Labor Energy (0.1394 and 0.9008), Fuel energy (0.1514 and 0.8913), Total Machinery Cost (TMC) (0.1492 and 0.9128), Total Machinery Energy (0.1378 and 0.9103).Respectively, while these parameters for ANN model were, to Labor Energy (0.0159 and 0.9990), Fuel energy (0.0206 and 0.9983), Total Machinery Cost (0.0287 and 0.9966), Total Machinery Energy (0.0157 and 0.9990) respectively, while these parameters for Sensitivity analysis model were, to Labor Energy (0.1899 and 0.8631), Fuel energy (0.8562 and 0.0206), Total Machinery Cost (0.1946 and 0.8581), Total Machinery Energy (0.1892 and 0.8437) respectively, respectively, while these parameters for ANFIS model were, to Labor Energy (0.0159 and 0.9990), Fuel energy (0.0206 and 0.9983), Total Machinery Cost (0.0287 and 0.9966), Total Machinery\ Energy (0.0157 and 0.9990) respectively, Results showed that ICA_ANN with seven neurons in hidden layer had better. According to the results of Sensitivity Analysis, only three parameters; Density, Soil Compressibility Factor and, Embankment Volume Index had significant effect on fuel consumption. According to the results of regression, only three parameters; Slope, Cut-Fill Volume (V) and, Soil Swelling Index (SSI) had significant effect on energy consumption. Using adaptive neuro-fuzzy inference system for prediction of labor energy, fuel energy, total machinery cost, and total machinery energy can be successfully demonstrated.

Biography :

Alzoubi has completed his PhD at the age of 40 years Tehran University and postdoctoral studies from Tehran University School of Surveying Geospatial Engineering-Department of Surveying and Geomatics Engineering. He is the director at the Directorate of Engineering and Transportation, a premier service organization. He has published more than 15 papers in reputed journals and has been serving as an editorial board member of repute. He Opening and studying the financial offers and the organization of the fundamental record, supervising the efficiency of electrical generators at Nseeb border center, and Supervising the efficiency of agricultural machinery at the ministry of agriculture.