Biosensors: An important tool to detect bacterial pathogens

Journal of Bioengineering & Biomedical Science

ISSN: 2155-9538

Open Access

Biosensors: An important tool to detect bacterial pathogens

3rd International Conference on Medical Physics & Biomedical Engineering

November 07-08, 2016 Barcelona, Spain

Sankar Narayan Sinha and Karabi Biswas

University of Kalyani, India

Posters & Accepted Abstracts: J Bioengineer & Biomedical Sci

Abstract :

A biosensor is an analytical instrument employed for the detection of an analytes, where a biological component is combined with a physicochemical detector. The present paper focuses as overview of various physical and chemical techniques viz., fluorescence and infrared spectroscopy, chromatography, flow cytometry and chemiluminescence as a basis for the construction of biosensor to identify the pathogenic bacteria. A thorough discussion of publications dealing with biosensor for detection of bacteria has been made in this paper. This review indicates current advances of alternative enzyme development to detect bacterial pathogens in clinical diagnosis and environmental monitoring. Enzyme, nucleic acid and antibody- based biosensors have been discussed based on biological treatment employed. On the basis of basic transducer principles, recent advance in biosensing technology that use electrochemical, piezoelectric, acoustic, optical and thermal biosensor are discussed for the detection of pathogenic bacteria. Special emphasis is given to methods to improve the analytical parameters of biosensor including analysis time and sensitivity as well as automation of assay procedure. Current developments in flow injection, immuno-filtration and flow through biosensor for bacterial detection are overviewed from the system├ó┬?┬?s engineering point of view. Future prospects for biosensor developments and problems associated with the commercialization of bacterial biosensor are discussed in details.

Biography :


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Citations: 307

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