Acute Administration of Aqueous Extract of Garcinia Kola Seed on Daily Blood Glucose Level and Selected Biochemical Indices of Liver Function in Albino Rats

9^th International Conference and Expo on Pharmacognosy, Medicinal Plants and Natural Products

August 03-04, 2022 | Webinar

Chinedu Imo

Faculty of Pure and Applied Sciences, Federal University Wukari

Scientific Tracks Abstracts: J Pharmacogn Nat Prod

Abstract :

This study evaluated the effects of acute administration of aqueous extract of Garcinia kola seed on daily blood glucose level and selected biochemical indices in wistar albino rats in connection with human health. The serum liver enzymes activities of ALT and ALP increased significantly (p<0.05) in the test animals (in groups two and three), while AST also increased, though not significantly (p>0.05). ALT increased from 35.38 ± 1.35 U/L in control group (group one) to 47.25 ± 1.71 U/L in group three, while AST and ALP increased from 36.75 ± 2.50 U/L to 38.25 ± 4.79 U/L and 27.46 ± 4.57 U/L to 40.14 ± 7.26 U/L respectively. Blood glucose level decreased on daily basis after administration of aqueous extract of Garcinia kola seed. The results showed that daily consumption of Garcinia kola seed induced hypoglycaemic effect and hepatic toxicity in Wistar albino rats as observed in groups two and three. This invariably implies that this Garcinia kola seed may be used in the management of hyperglycaemia. Also, it should not be consumed regularly on daily basis. Keywords: Blood glucose, Garcinia kola, liver enzymes and life expectancy.

Biography :

Chinedu Imo was born on 26 June 1983 in Orlu, Imo, Nigeria. He is a Nigerian Musical Artist, Gospel singer, and Author. He has collaborated with a number of labels, including Favuor Music Nig. Chinedu has worked on a variety of projects during his career.