A decade of multi-drug resistant N. gonorrhoea in Coventry, UK 2007 to 2016

Journal of AIDS & Clinical Research

ISSN: 2155-6113

Open Access

A decade of multi-drug resistant N. gonorrhoea in Coventry, UK 2007 to 2016



P Sris Allan

Coventry & Warwickshire Partnership Trust, UK

Scientific Tracks Abstracts: J AIDS Clin Res

Abstract :

Antibiotic resistance to Neisseria gonorrhea (N. gonorrhea) is rapidly developing and changing worldwide. Soon, we may be faced with a situation where parenteral treatment is the only option. All N. gonorrhea cases in our clinic within 1st January to 30th June 2007 to 2016 were identified and analyzed for antibiotic sensitivity. In 2016, there were 131 cases of N. gonorrhea identified. Since the introduction of Ceftriaxone and Azithromycin as the treatment of choice in 2011, we saw a reduction in multi-drug resistance until 2013, after which point we saw a gradual increase in cases reaching 23% in 2016. This is the first year we have identified the isolate resistant to four antibiotic groups including cefuroxime. Age, past-history of GC and past-history of chlamydia were further analyzed in patients who were diagnosed with N. gonorrhea infection in 2016. Multi drug-resistant (MDR) GC infected patients are more likely to be older compared to fully sensitive N. gonorrhea infected patients, mean age 30 vs. 24 (P=0.02). Interestingly past-history of N. gonorrhea infection is not statistically significant between the groups but past history of chlamydia is associated with an increased risk of MDR N. gonorrhoea (P=0.05). The emergence of cephalosporin resistance is a worrying trend. Continued close monitoring with research to identify new treatment is urgently needed. Further research to predict MDR N. gonorrhoea infection is an urgent priority for the international scientific community.

Biography :

P Sris Allan is a consultant in Sexual health and HIV in Coventry, UK and an associate professor in Warwick medical school. He has been active in clinical practice, medical education and in the field of HIV research particularly HIV and ageing.

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