3-Nitro-2-(trihalomethyl)-2H-chromenes in Reactions with 1,3-Dipoles: Synthesis and Cytotoxic Activity of ∆3-Annulated Chromane Derivatives

2^nd International Conference on PHARMACEUTICAL CHEMISTRY

October 02-04, 2017 Barcelona, Spain

Vladislav Yu Korotaev, Nikolay S Zimnitskiy, Igor B Kutyashev, Alexey Yu Barkov and Vyacheslav Ya Sosnovskikh

Ural Federal University, Russia

Scientific Tracks Abstracts: Med Chem (Los Angeles)

Abstract :

The [3+2] cycloaddition of sodium azide and stabilized azomethine ylides to 3-nitro-2-(trihalomethyl)-2H-chromenes 1 and 2 was studied and cycloadducts 3�8 were synthesized.

Biography :

Korotaev V Yu graduated from the Ural State University in 1993 and has completed his PhD in 1998. Currently he works at the Department of Organic Chemistry of the Ural Federal University as a senior researcher. He has published more than 65 papers in peer-reviewed journals. His area of scientific interests includes unsaturated nitro compounds, heterocyclic compounds and fluoroorganic chemistry.