Short Communication - (2025) Volume 10, Issue 3
Received: 01-Aug-2025, Manuscript No. jibdd-25-174842;
Editor assigned: 04-Aug-2025, Pre QC No. P-174842;
Reviewed: 18-Aug-2025, QC No. Q-174842;
Revised: 22-Aug-2025, Manuscript No. R-174842;
Published:
29-Aug-2025
, DOI: 10.37421/2476-1958.2025.10.260
Citation: Romano, Francesca. ”Genetics: Personalized Care for Improved Health.” J Inflamm Bowel Dis 10 (2025):260.
Copyright: © 2025 Romano F. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution and reproduction in any medium, provided the original author and source are credited.
Understanding how our genes influence the risk of developing Type 2 Diabetes Mellitus is critical. This review dives into the complex interplay of various genetic markers and their impact, highlighting that while lifestyle plays a role, underlying genetic predispositions significantly increase vulnerability, making early screening and personalized interventions more effective.[1] Schizophrenia, a complex psychiatric disorder, has a strong genetic component. This article focuses on copy number variations (CNVs) and their role in increasing genetic predisposition. It highlights how these subtle changes in our DNA can significantly influence risk, providing insights into the biological underpinnings and potential avenues for earlier diagnosis or targeted therapies.[2] Understanding the genetic underpinnings of autoimmune diseases like rheumatoid arthritis is crucial for better treatment. This paper explores how specific gene variants contribute to an individual's predisposition, influencing disease onset and progression. What this really means is that tailoring treatments based on a patient's genetic profile could lead to more effective and personalized care.[3] Coronary artery disease remains a leading cause of mortality, and our genetic makeup plays a significant role in determining individual risk. This research highlights specific genetic markers and pathways that confer a predisposition to the condition, suggesting that identifying these early could enable more targeted preventive strategies and personalized risk assessments, moving beyond traditional risk factors.[4] Breast cancer is a complex disease where genetic predisposition accounts for a significant portion of cases. This article explores newly identified genetic variants and established high-penetrance genes that increase susceptibility. What this means is that understanding these genetic blueprints helps in risk stratification, offering opportunities for personalized screening protocols and preventative measures for at-risk individuals.[5] Parkinson's disease, a progressive neurodegenerative disorder, has a recognized genetic component. This study investigates various genetic factors that contribute to an individual's predisposition to developing the condition, beyond just the well-known genes. Here's the thing: identifying these subtle genetic influences helps us piece together the complex puzzle of Parkinson's, potentially paving the way for earlier detection and novel therapeutic targets.[6] Susceptibility to infectious diseases isn't solely about exposure; our genes play a critical role. This paper examines how genetic predispositions influence the severity and outcome of infections, specifically focusing on viral pathogens. What this really means is that understanding these genetic variances could help identify individuals at higher risk for severe disease, allowing for more targeted prevention and treatment strategies during outbreaks.[7] Our genetic makeup significantly influences how our bodies respond to medications, a field known as pharmacogenomics. This study explores how specific genetic predispositions can alter drug metabolism and efficacy, impacting treatment outcomes. What this means for us is the potential for personalized medicine, where drug dosages and choices are tailored to an individual's genetic profile, maximizing benefits and minimizing adverse reactions.[8] Obesity is a complex health issue influenced by both environmental factors and our genes. This research delves into the genetic predispositions that increase an individual's susceptibility to obesity, exploring various candidate genes and their roles in metabolism and appetite regulation. Let's break it down: identifying these genetic markers can lead to more targeted interventions and preventative strategies, moving beyond a one-size-fits-all approach.[9] Understanding the genetic underpinnings of depression and anxiety is crucial for developing more effective treatments. This article explores how inherited genetic factors contribute to an individual's predisposition to these mental health conditions. What this really means is that by pinpointing specific genetic markers, we can move towards more personalized diagnostic tools and therapeutic approaches, potentially improving patient outcomes.[10]
Our genetic makeup is a significant determinant in individual disease risk and treatment efficacy. Understanding how our genes influence the risk of developing Type 2 Diabetes Mellitus is critical. This review dives into the complex interplay of various genetic markers and their impact, highlighting that while lifestyle plays a role, underlying genetic predispositions significantly increase vulnerability, making early screening and personalized interventions more effective [1].
Focusing on chronic conditions, coronary artery disease remains a leading cause of mortality, and our genetic makeup plays a significant role in determining individual risk. Research highlights specific genetic markers and pathways that confer a predisposition to the condition, suggesting that identifying these early could enable more targeted preventive strategies and personalized risk assessments, moving beyond traditional risk factors [4]. Additionally, obesity is a complex health issue influenced by both environmental factors and our genes. This research delves into the genetic predispositions that increase an individual's susceptibility to obesity, exploring various candidate genes and their roles in metabolism and appetite regulation. Let's break it down: identifying these genetic markers can lead to more targeted interventions and preventative strategies, moving beyond a one-size-fits-all approach [9].
In the realm of neurological and mental health, Schizophrenia, a complex psychiatric disorder, has a strong genetic component. This article focuses on copy number variations (CNVs) and their role in increasing genetic predisposition. It highlights how these subtle changes in our DNA can significantly influence risk, providing insights into the biological underpinnings and potential avenues for earlier diagnosis or targeted therapies [2]. Parkinson's disease, a progressive neurodegenerative disorder, also has a recognized genetic component. This study investigates various genetic factors that contribute to an individual's predisposition, beyond just the well-known genes. Here's the thing: identifying these subtle genetic influences helps us piece together the complex puzzle of Parkinson's, potentially paving the way for earlier detection and novel therapeutic targets [6]. Understanding the genetic underpinnings of depression and anxiety is crucial for developing more effective treatments. Inherited genetic factors contribute to an individual's predisposition to these mental health conditions. What this really means is that by pinpointing specific genetic markers, we can move towards more personalized diagnostic tools and therapeutic approaches, potentially improving patient outcomes [10].
Our genes are also central to autoimmune conditions and cancer. Understanding the genetic underpinnings of diseases like rheumatoid arthritis is crucial for better treatment. This paper explores how specific gene variants contribute to an individual's predisposition, influencing disease onset and progression. What this really means is that tailoring treatments based on a patient's genetic profile could lead to more effective and personalized care [3]. Breast cancer is a complex disease where genetic predisposition accounts for a significant portion of cases. This article explores newly identified genetic variants and established high-penetrance genes that increase susceptibility. What this means is that understanding these genetic blueprints helps in risk stratification, offering opportunities for personalized screening protocols and preventative measures for at-risk individuals [5].
Finally, susceptibility to infectious diseases isn't solely about exposure; our genes play a critical role. This paper examines how genetic predispositions influence the severity and outcome of infections, specifically focusing on viral pathogens. What this really means is that understanding these genetic variances could help identify individuals at higher risk for severe disease, allowing for more targeted prevention and treatment strategies during outbreaks [7]. Our genetic makeup significantly influences how our bodies respond to medications, a field known as pharmacogenomics. This study explores how specific genetic predispositions can alter drug metabolism and efficacy, impacting treatment outcomes. What this means for us is the potential for personalized medicine, where drug dosages and choices are tailored to an individual's genetic profile, maximizing benefits and minimizing adverse reactions [8].
Our genetic blueprint significantly influences vulnerability to a wide array of health conditions, underscoring the shift towards personalized medicine. This collection of reviews highlights how genetic predispositions play a crucial role across various diseases, from chronic metabolic disorders like Type 2 Diabetes Mellitus to complex psychiatric conditions such as Schizophrenia. It delves into the genetic underpinnings of autoimmune diseases like rheumatoid arthritis and critical health issues such as coronary artery disease and breast cancer. Furthermore, the data explores genetic factors in neurodegenerative conditions like Parkinson's disease, susceptibility to severe infectious diseases, and even individual responses to medications, a field known as pharmacogenomics. The genetic component in conditions like obesity and mental health disorders like depression and anxiety is also examined. The overarching theme is that understanding these inherent genetic influences is pivotal. It allows for the identification of at-risk individuals, enabling more effective early screening, personalized preventive strategies, and tailored interventions. This knowledge moves us beyond a one-size-fits-all approach, paving the way for more precise diagnostics and therapeutic development. Ultimately, deciphering our genetic code holds the key to improving patient outcomes by customizing care based on individual biological profiles.
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