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Uremic Cardiomyopathy Open Access Articles | Open Access Journals

Journal of Interventional and General Cardiology

ISSN: 2684-4591

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Uremic Cardiomyopathy Open Access Articles

Cardiovascular disease is the leading cause of morbidity and mortality in chronic kidney disease (CKD). Left ventricular hypertrophy (LVH) is the most prevalent cardiac abnormality in these patients and is closely related to mortality. This adverse cardiac fallout is consequence of the underlying CKD-related cardiomyopathy, which has been termed “Uremic Cardiomyopathy”. However, the pathogenesis of uremic cardiomyopathy is multifactorial and is poorly understood.Despite advances in dialysis treatment and in the improved management of hypertension, hypervolemia, anemia, and chronic kidney disease—mineral and bone disorder (CKD-MBD), patients with CKD continue to have abnormal myocardial remodeling, which results in the persistently high rates of cardiovascular events and mortality.In the last two decades, two new components of CKD-MBD have been pinpoint the hormone FGF23, and its cofactor, αKlotho. FGF23 is deleterious to the myocardium, while αKlotho is vigilant. Although αKlotho is an obligatory cofactor for FGF23 action as the underlying phosphaturic hormone in phosphorus homeostasis, the two seem to have independent and antagonistic effects on the myocardium.

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Survival analysis and characterization of ATP binding cassette (ABC) drug transporters and their role in breast cancer chemotherapy treatment using in silico approach
Mohammed Hashim Abdalraheem Hassan, Ashley Pretoruis and Marius B Tincho
Posters & Accepted Abstracts: Cancer Science & Therapy
Survival analysis and characterization of ATP binding cassette (ABC) drug transporters and their role in breast cancer chemotherapy treatment using in silico approach
Mohammed Hashim Abdalraheem Hassan, Ashley Pretoruis and Marius B Tincho
Posters & Accepted Abstracts: Cancer Science & Therapy
Molecular dynamics simulation on the low sensitivity of Y352H, 1310N mutants of NEDD-8 activating enzyme(NAE) for MLN4924 inhibitor as a cancer drug
Behnam Rashidieh
Posters-Accepted Abstracts: Cancer Science & Therapy
Molecular dynamics simulation on the low sensitivity of Y352H, 1310N mutants of NEDD-8 activating enzyme(NAE) for MLN4924 inhibitor as a cancer drug
Behnam Rashidieh
Posters-Accepted Abstracts: Cancer Science & Therapy
TREM-1 expression in leukemia and a functional link between leukemia and TREM-1 in stem/progenitor cells and microvesicles
Wenying Li, Xiaoling Yi, Wei Liu, Li Jiang, Cu Lu, Shiang Huang and Huiyu Li
Accepted Abstracts: Cancer Science & Therapy
TREM-1 expression in leukemia and a functional link between leukemia and TREM-1 in stem/progenitor cells and microvesicles
Wenying Li, Xiaoling Yi, Wei Liu, Li Jiang, Cu Lu, Shiang Huang and Huiyu Li
Accepted Abstracts: Cancer Science & Therapy
Aquaporin 5 (AQP5) activates the epidermal growth factor receptor (EGFR) and Src, potentially through its novel kinase activity, and may be involved in Iressa resistance
Chulso Moon
Scientific Tracks Abstracts: Cancer Science & Therapy
Aquaporin 5 (AQP5) activates the epidermal growth factor receptor (EGFR) and Src, potentially through its novel kinase activity, and may be involved in Iressa resistance
Chulso Moon
Scientific Tracks Abstracts: Cancer Science & Therapy
The effects of night sleep following mental imagery on a goal-based task learning
Mohsen Afrouzeh
Posters-Accepted Abstracts: Journal of Sports Medicine & Doping Studies
The effects of night sleep following mental imagery on a goal-based task learning
Mohsen Afrouzeh
Posters-Accepted Abstracts: Journal of Sports Medicine & Doping Studies

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Citations: 11

Journal of Interventional and General Cardiology received 11 citations as per Google Scholar report

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