DNA of human spermatozoa are often subject to varied sorts of modifications acquired throughout life. Put simply, two basic sorts of acquired sperm DNA modifications are often distinguished: genetic and epigenetic. Genetic modifications cause alterations of the DNA sequence and mainly result from the formation of breakpoints resulting in sperm DNA fragmentation. Epigenetic modifications include a huge spectrum of events that influence the expression of various genes without altering their DNA sequence. Both the genetic and therefore the epigenetic modifications of sperm DNA can negatively influence embryonic development, cause miscarriages, and be the origin of various health problems for the offspring. on sperm DNA fragmentation, reliable diagnostic methods are currently available. On the opposite hand, the detection of probably harmful epigenetic modifications in spermatozoa may be a far more complicated issue.
Scientific Tracks Abstracts: Molecular and Genetic Medicine
Scientific Tracks Abstracts: Molecular and Genetic Medicine
Scientific Tracks Abstracts: Molecular and Genetic Medicine
Scientific Tracks Abstracts: Molecular and Genetic Medicine
Scientific Tracks Abstracts: Molecular and Genetic Medicine
Scientific Tracks Abstracts: Molecular and Genetic Medicine
Scientific Tracks Abstracts: Journal of Molecular Biomarkers & Diagnosis
Scientific Tracks Abstracts: Molecular Biomarkers & Diagnosis
Scientific Tracks Abstracts: Journal of Tissue Science and Engineering
Scientific Tracks Abstracts: Journal of Tissue Science and Engineering
Journal of Genetics and DNA Research received 3 citations as per Google Scholar report