Because of the movement of the drugs after death, postmortem concentrations in the blood may not always reflect antemortem concentrations in the blood.
The socalled Postmortem Redistribution (PMR) phenomenon. Mechanisms involved in redistribution post mortem are both complex and poorly understood. However, blood concentrations of postmortem drugs follow some widely accepted trends which help with interpretation; the characteristics of the drug itself can be used to indicate whether a drug is subject to PMR.
For simple, lipophilic drugs with a high volume of delivery (> 3L / kg),significant changes in blood drug concentrations are forecasted.
Postmortem toxicology is the study of the presence, distribution, and quantification after death of a xenobiotic. By its quantification and distribution in the body at the time of autopsy, this information is used to compensate for the physiological effects of a xenobiotic upon death.
Research Article: Journal of Forensic Research
Research Article: Journal of Forensic Research
Research Article: Journal of Forensic Research
Research Article: Journal of Forensic Research
Research Article: Journal of Forensic Research
Research Article: Journal of Forensic Research
Case Report: Journal of Forensic Research
Case Report: Journal of Forensic Research
Research Article: Journal of Forensic Research
Research Article: Journal of Forensic Research
Review Article: Journal of Forensic Research
Review Article: Journal of Forensic Research
Posters & Accepted Abstracts: Cancer Science & Therapy
Posters & Accepted Abstracts: Cancer Science & Therapy
Scientific Tracks Abstracts: Cancer Science & Therapy
Scientific Tracks Abstracts: Cancer Science & Therapy
Scientific Tracks Abstracts: Journal of Forensic Research
Scientific Tracks Abstracts: Journal of Forensic Research
Scientific Tracks Abstracts: Journal of Sports Medicine & Doping Studies
Scientific Tracks Abstracts: Journal of Sports Medicine & Doping Studies
Posters & Accepted Abstracts: Journal of Dermatology and Dermatologic Diseases
Posters & Accepted Abstracts: Journal of Dermatology and Dermatologic Diseases
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