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Pharmacoproteomics Research Articles | Open Access Journals

Journal of Pharmacognosy & Natural Products

ISSN: 2472-0992

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Pharmacoproteomics Research Articles

Experimental workflows in proteomics approaches to drug screening and development, like genomics approaches, may be broadly classified as targeted or global. Targeted approaches may involve affinity-based or activity-based profiling techniques, which employ chemically-engineered probes to capture proteins of interest. While global methods are more challenging from a bioinformatics standpoint, they are advantageous because they provide unbiased, large-scale analyses and may reveal unexpected relationships among seemingly unrelated pathways. A typical in vitro workflow involves treating cells with the drug of interest, lysing the cells, digesting proteins into peptides, and then analyzing the entire proteome by mass spectrometry techniques. Drug failure is often due to poor pharmacokinetic properties such as low bioavailability, poor absorption, pre-mature metabolism, or adverse side effects.
Pharmacoproteomics gives us the potential to study drug mechanisms at the proteome level while at the same time investigating toxicity and resistance, or perhaps discovering new drug targets, early in the drug development process. In this manner, drugs with flawed properties can be saved from further development, while newer, better-performing drugs can be discovered and moved forward.

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Conference Proceedings

Pharmacovigilance monitoring in social media: Challenge, facts and solution
Tarik Messaoud
Keynote: Journal of Formulation Science & Bioavailability
Pharmacovigilance monitoring in social media: Challenge, facts and solution
Tarik Messaoud
Keynote: Journal of Formulation Science & Bioavailability
Immune modulatory and anti-inflammatory activities of a PDE -inhibitor and its solvent
Romany Helmy Thabet
Posters & Accepted Abstracts: Pharmaceutical Regulatory Affairs: Open Access
Immune modulatory and anti-inflammatory activities of a PDE -inhibitor and its solvent
Romany Helmy Thabet
Posters & Accepted Abstracts: Pharmaceutical Regulatory Affairs: Open Access
Bio-surfactant from Paenibacillus dendritiformis and its application in assisting polycyclic aromatic hydrocarbon (PAH) and motor oil sludge removal from contaminated soil and sand media
Fisseha Andualem Bezza and Evans M Nkhalambayausi Chirwa
Posters-Accepted Abstracts: Journal of Bioprocessing & Biotechniques
Bio-surfactant from Paenibacillus dendritiformis and its application in assisting polycyclic aromatic hydrocarbon (PAH) and motor oil sludge removal from contaminated soil and sand media
Fisseha Andualem Bezza and Evans M Nkhalambayausi Chirwa
Posters-Accepted Abstracts: Journal of Bioprocessing & Biotechniques
Optimization of fermentation conditions for Teff (Eragrostis tef) malt wort using response surface methodology
Mekonnen M Gebremariam, Ahmed Hassani, Martin Zarnkow and Thomas Becker
Posters-Accepted Abstracts: Journal of Bioprocessing & Biotechniques
Optimization of fermentation conditions for Teff (Eragrostis tef) malt wort using response surface methodology
Mekonnen M Gebremariam, Ahmed Hassani, Martin Zarnkow and Thomas Becker
Posters-Accepted Abstracts: Journal of Bioprocessing & Biotechniques
Changing landscape of healthcare, regulations and role of RA
Rama K. Pidaparti
Keynote: Pharmaceutical Regulatory Affairs: Open Access
Changing landscape of healthcare, regulations and role of RA
Rama K. Pidaparti
Keynote: Pharmaceutical Regulatory Affairs: Open Access
Method development and validation of the assay and dissolution of a fixed dose combination of tenofovir and efavirenz tablet
Divya Sree, Thadkapally Srinivas and Aramalla Eashwar Rao
Accepted Abstracts: Pharmaceutical Regulatory Affairs: Open Access
Method development and validation of the assay and dissolution of a fixed dose combination of tenofovir and efavirenz tablet
Divya Sree, Thadkapally Srinivas and Aramalla Eashwar Rao
Accepted Abstracts: Pharmaceutical Regulatory Affairs: Open Access
Targeted gene therapy for the treatment of heart failure
B. Shruthi, K. Mounika and P.K.Lakshmi
Posters: Pharmaceutical Regulatory Affairs: Open Access
Targeted gene therapy for the treatment of heart failure
B. Shruthi, K. Mounika and P.K.Lakshmi
Posters: Pharmaceutical Regulatory Affairs: Open Access
Agtuzumab, a humanized monoclonal antibody blocks AGR2 function through conformational epitopes around its catalytic center
Dawei Li
Scientific Tracks Abstracts: Pharmaceutical Regulatory Affairs: Open Access
Agtuzumab, a humanized monoclonal antibody blocks AGR2 function through conformational epitopes around its catalytic center
Dawei Li
Scientific Tracks Abstracts: Pharmaceutical Regulatory Affairs: Open Access

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Citations: 606

Journal of Pharmacognosy & Natural Products received 606 citations as per Google Scholar report

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