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Osteoporotic Spine Innovations | Open Access Journals
Journal of Bioanalysis & Biomedicine

Journal of Bioanalysis & Biomedicine

ISSN: 1948-593X

Open Access

Osteoporotic Spine Innovations

Osteoporosis has become a major medical problem as the world's aging population grows rapidly. Osteoporosis predisposes patients to fractures, progressive spinal deformities and stenosis, and is a major concern before performing spine surgery, especially with bone fusions and instruments. Osteoporosis has often been considered a contraindication for spine surgery, while in some cases patients have undergone limited and inadequate procedures to avoid concomitant instrumentation.
Current treatments for osteoporosis have focused on stopping the activity of osteoclastic cells. In particular, the treatment of osteoporosis has focused on the administration of drugs called "anti-resorptive agents" or ARBs. The most common classes of anti-resorptive drugs include estrogens, selective estrogen receptor modulators (SERMs), biphosphonates, calcitonin, osteoprotegrin (OPG), cathespine K and statins. Current products include FOSAMAX® (alendronate) in the United States, Biphosphonate DIDRONEL® (etidronate) and ACTONEL® (risedronate).
As the population ages and the expectations of older patients increase, the demand for surgical treatment in older patients with osteoporosis and degenerative diseases of the spine becomes progressively greater. Today, advances in surgical and anesthetic technology make it possible to operate successfully on elderly patients who no longer accept disabling physical conditions. This article discusses the biomechanics of the osteoporotic spine, the diagnosis and management of osteoporotic patients with the spine, as well as new treatments, recommendations, surgical indications, strategies and instrumentation in patients with osteoporosis who need spine operations.

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Citations: 3099

Journal of Bioanalysis & Biomedicine received 3099 citations as per Google Scholar report

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