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Osteonecrosis Peer-review Journals | Open Access Journals
Journal of Biomedical Systems & Emerging Technologies

Journal of Biomedical Systems & Emerging Technologies

ISSN: 2952-8526

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Osteonecrosis Peer-review Journals

Osteonecrosis is a bone condition that can be a long-term complication of childhood cancer therapy. It results from the temporary or permanent interruption of blood flow to the affected bone. Due to the loss of blood, the bone tissue dies and causes the bone to collapse.

 Although several theories have been proposed, no pathophysiological mechanism has been identified as the etiology of the development of osteonecrosis of the femoral head. However, the basic mechanism involves impaired circulation to a specific area which ultimately becomes necrotic. A variety of non-operative regimens have been evaluated for the treatment of the disease before collapse, with varying success. Prospective, multicenter, randomized trials are needed to assess the effectiveness of these regimens in modifying the natural history of the disease. Joint preservation procedures are indicated in the treatment of pre-collapse disease, with several studies showing positive results in the medium and long term. long-term follow-up.

 Studies on total joint replacement, after collapse of the femoral head, have described excellent results after more than ten years of follow-up, which is a major advance and has led to a paradigm shift in treatment of these patients. the resurfacing arthroplasty was suboptimal and these procedures limited the indications in patients with osteonecrosis of the femoral head.

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Citations: 43

Journal of Biomedical Systems & Emerging Technologies received 43 citations as per Google Scholar report

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