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Oral Bioavailability Open Access Journals | Open Access Journals
Pharmacoeconomics: Open Access

Pharmacoeconomics: Open Access

ISSN: 2472-1042

Open Access

Oral Bioavailability Open Access Journals

The Drug oral bioavailability is the fractional extent of a drug dosage that finally reaches to the therapeutic site of action and it is quantitatively symbolized as %F. In many cases, most of the orally administered drug is metabolized and eliminated before reaching systemic blood circulation. Therefore, poor bioavailability may cause a new drug to fail clinical trials, even if it has high efficacy in previous in vitro and/or in vivo tests. The traditional process for measuring the %F of a drug is expensive, costly, and time-consuming. Using computational methods as an alternative to calculating the %F of new drug candidates, even before synthesizing the compound, would be advantageous by saving resources and provides a promising alternative to traditional experimental protocols.

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Relevant Topics in Pharmaceutical Sciences

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