New Finding On Target Based Drug Discovery

Drug design which is also known as rational drug design, is the process of inventive of finding the new medications based on the the knowledge of a biological target. Drug design usually defines the designing of the molecules that are complementary in shape and charges to the bimolecular target with which they interacts and then will bind it. Some of the therapeutic agents are likely to be effective in a specific patients who may have an underlying disorder which is responsive to the manipulation of the dose levels of the same agent or several other different agents. AS per the study this indicates that there are three kinds of enrichment. They are noise reduction, prognostic and predictive. Target discovery, that incorporates the identification and early validation of the disease-modifying targets, is a very important and significant primary step in the drug discovery field.

High Impact List of Articles

Discovery of Autophagy-Inducing Chloroquine Analogs with Potent Anticancer Activity in Breast Cancer Cells
Yasser Heakal*, Dhvani Patel, Peter Cao, Catherine C. Lincourt, Ashley OÃÂ¢Ãâ¬Ãâ¢Leary and Dominic L. Ventura
Research Article: Medicinal Chemistry
Discovery of Autophagy-Inducing Chloroquine Analogs with Potent Anticancer Activity in Breast Cancer Cells
Yasser Heakal*, Dhvani Patel, Peter Cao, Catherine C. Lincourt, Ashley OÃÂ¢Ãâ¬Ãâ¢Leary and Dominic L. Ventura
Research Article: Medicinal Chemistry
Protection against Advanced Glycation End Products and the Mode of Action of Lemon Balm on Hemoglobin Fructose-Mediated Glycation
Mehran Miroliaei, Peymaneh Shafaei, Akram Aminjafari, Danial Barati, Riley Meekins, Safaa Kader, Kostelnik J. Colton and Esmaiel Jabbari
Research Article: Medicinal Chemistry
Protection against Advanced Glycation End Products and the Mode of Action of Lemon Balm on Hemoglobin Fructose-Mediated Glycation
Mehran Miroliaei, Peymaneh Shafaei, Akram Aminjafari, Danial Barati, Riley Meekins, Safaa Kader, Kostelnik J. Colton and Esmaiel Jabbari
Research Article: Medicinal Chemistry
Novel Route for Synthesis of Antihypertensive Activity of Tetrazole Analogues as a Carbamate and Urea Derivatives
Ramakrishna Vellalacheruvu, Sai Leela R and Ravindranath LK
Research Article: Medicinal Chemistry
Novel Route for Synthesis of Antihypertensive Activity of Tetrazole Analogues as a Carbamate and Urea Derivatives
Ramakrishna Vellalacheruvu, Sai Leela R and Ravindranath LK
Research Article: Medicinal Chemistry
Design, Synthesis, Computer Modeling and Analgesic Activity of Some New Disubstituted Quinazolin-4(3H)-ones
Rezk A Ayyad, Helmy M Sakr and Kamal M El- Gamal
Research Article: Medicinal Chemistry
Design, Synthesis, Computer Modeling and Analgesic Activity of Some New Disubstituted Quinazolin-4(3H)-ones
Rezk A Ayyad, Helmy M Sakr and Kamal M El- Gamal
Research Article: Medicinal Chemistry
Proximate Chemical Composition and Antimicrobial Activities of Fixed oils from Diospyros lotus L.
Ghias Uddin, Abdur Rauf, Bina Shaheen Siddiqui, Mohammad Arfan, Inayat-Ur-Rahman and Inamullah Khan
Research Article: Medicinal Chemistry
Proximate Chemical Composition and Antimicrobial Activities of Fixed oils from Diospyros lotus L.
Ghias Uddin, Abdur Rauf, Bina Shaheen Siddiqui, Mohammad Arfan, Inayat-Ur-Rahman and Inamullah Khan
Research Article: Medicinal Chemistry

Conference Proceedings

A Western pedagogy from an eastern context: reflections from a trans-national chemistry education research project
Sheila Qureshi
Posters & Accepted Abstracts: Chemical Sciences Journal
A Western pedagogy from an eastern context: reflections from a trans-national chemistry education research project
Sheila Qureshi
Posters & Accepted Abstracts: Chemical Sciences Journal
Fluorescent probes for imaging of intracellular and in vivo ROS
Tao Yi
Posters & Accepted Abstracts: Chemical Sciences Journal
Fluorescent probes for imaging of intracellular and in vivo ROS
Tao Yi
Posters & Accepted Abstracts: Chemical Sciences Journal
An attractor-repulsor molecular design prinicple for the exploration of supramolecular Steric Hindrance (SSH) effects
Linghai Xie
Scientific Tracks Abstracts: Chemical Sciences Journal
An attractor-repulsor molecular design prinicple for the exploration of supramolecular Steric Hindrance (SSH) effects
Linghai Xie
Scientific Tracks Abstracts: Chemical Sciences Journal
Utilizing eco-friendly nanoparticle techniques in improving drug deliver
Shaaban K Mohamed, Mohamed A Mohamed and Nivien A Nafady
Scientific Tracks Abstracts: Medicinal Chemistry
Utilizing eco-friendly nanoparticle techniques in improving drug deliver
Shaaban K Mohamed, Mohamed A Mohamed and Nivien A Nafady
Scientific Tracks Abstracts: Medicinal Chemistry
Synthesis and characterization of 2-((4R,4aR,5aS,6S)-1,3-dioxo3m3a,4,4a,5,5a6,6a-octahydro-4,6- ethenocyclopropa[f]isoindol-2(1H)-yl)-N-(substituted phenyl) acetamides anticipated to have HIV- 1 activity
Abdulmajeed S H AlSamarrai and Noor H Abdulla
Scientific Tracks Abstracts: Medicinal Chemistry
Synthesis and characterization of 2-((4R,4aR,5aS,6S)-1,3-dioxo3m3a,4,4a,5,5a6,6a-octahydro-4,6- ethenocyclopropa[f]isoindol-2(1H)-yl)-N-(substituted phenyl) acetamides anticipated to have HIV- 1 activity
Abdulmajeed S H AlSamarrai and Noor H Abdulla
Scientific Tracks Abstracts: Medicinal Chemistry

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Medicinal Chemistry